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Merck

1118350

USP

Chloroquine Related Compound D

United States Pharmacopeia (USP) Reference Standard

别名:

7-Chloro-4-{[4-(ethylamino)-1-methylbutyl]amino}quinoline, Monodesethylchloroqu​ine

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About This Item

经验公式(希尔记法):
C16H22ClN3
CAS号:
分子量:
291.82
MDL號碼:
分類程式碼代碼:
41116107
NACRES:
NA.24

生物源

synthetic

等級

pharmaceutical primary standard

agency

USP

API 家族

chloroquine

形狀

powder

包裝

pkg of 15 mg

製造商/商標名

USP

儲存條件

protect from light

顏色

tan

bp

343.4-347 °F (173—175°C; 845.06°F )

mp

176-215.6 °F (80—102°C)

溶解度

chloroform: soluble
dichloromethane: soluble

密度

1.14 g/cm3

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

SMILES 字串

ClC(C=C1)=CC2=C1C(NC(CCCNCC)C)=CC=N2

InChI

1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)

InChI 密鑰

MCYUUUTUAAGOOT-UHFFFAOYSA-N

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一般說明

Chloroquine Related Compound D is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

應用

Chloroquine Related Compound D USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Chloroquine Phosphate

分析報告

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他說明

Sales restrictions may apply.

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

防範說明

危險分類

Acute Tox. 4 Oral

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


分析证书(COA)

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HPLC with ultraviolet detection for the determination of chloroquine and desethylchloroquine in whole blood and finger-prick capillary blood dried on filter paper
Cheomung A and Na-Bangchang K
Journal of Pharmaceutical and Biomedical Analysis, 55(5), 1031-1040 (2011)
An HPLC method with diode array detector for the simultaneous quantification of chloroquine and desethylchloroquine in plasma and whole blood samples from Plasmodium vivax patients in Vietnam, using quinine as an internal standard
Van Pham T, et al.
Biomedical Chromatography, 30(7), 1104-1111 (2016)
Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Vincent MJ, et al.
Virology Journal, 2(1), 1-10 (2005)
Chloroquine Phosphate USP Monograph
USP43-NF38: United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 959-959 (2020)

实验方案

Chloroquine Phosphate HPLC Assay meets system suitability criteria with good resolution, reproducibility, and sensitivity.

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