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Merck

X4376

Sigma-Aldrich

黄嘌呤氧化酶 来源于牛奶

lyophilized powder, 0.4-1.0 units/mg protein

别名:

XOD, 木糖:氧氧化还原酶

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About This Item

CAS号:
EC 号:
1.17.3.2.
EC號碼:
MDL號碼:
分類程式碼代碼:
12352204
NACRES:
NA.54

生物源

bovine milk

形狀

lyophilized powder

比活性

0.4-1.0 units/mg protein

分子量

283 kDa

成份

Protein, 10.0-25.0%

儲存溫度

2-8°C

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一般說明

Formerly E.C.1.1.3.22

應用

来自牛奶的黄嘌呤氧化酶已被用作生成超氧化物的来源。它也已用作内部校准电化学连续酶测定(internally calibrated electrochemical continuous enzyme assay,ICECEA)中的模型酶。

生化/生理作用

异黄酮染料木素在0.1-4.0 μM的浓度范围内显示出对黄嘌呤氧化酶的抑制,高于5 μM的浓度则会激活黄嘌呤氧化酶。
木糖氧化酶是一种含钼酶,存在于细胞质中,能够被黄酮类化合物有效抑制。它在一些药物和嘌呤嘧啶代谢中有重要作用。它被认为是活性氧簇的生物来源。
黄嘌呤氧化酶可用作氧化应激的潜在生物标记。它还涉及组织和血管损伤,例如肝损伤、炎症性疾病和慢性心力衰竭。

單位定義

在pH7.5,25℃条件下,一个单位可每分钟将1.0 μmole黄嘌呤转化为尿酸。以次黄嘌呤为底物可获得约50%的活性。

外觀

含有0.5%的水杨酸钠。

分析報告

双缩脲法测蛋白

象形圖

Health hazard

訊號詞

Danger

危險聲明

防範說明

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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