The solution stability of this product has not been determined internally. Various sources state that solutions in DMSO or DMF may be stored at -20° for up to 3 months. The solution stability should be determined by the end-user.
W102
( R )-(+)-WIN 55,212-2 甲磺酸盐
≥98% (HPLC), powder, CB2 agonist
别名:
( R )-(+)-\ [2,3-二氢-5-甲基-3\ [（4-吗啉基）甲基] 吡咯并 \ [1,2,3-de]-1,4-苯并恶嗪基]-（1-萘基）甲酮 甲磺酸盐, WIN 55212-2 甲磺酸酯, WIN 552122 甲磺酸酯
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25 MG
$658.00
100 MG
$2,060.00
About This Item
线性分子式:
C27H26N2O3 · CH3SO3H
CAS号:
分子量:
522.61
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.77
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产品名称
( R )-(+)-WIN 55,212-2 甲磺酸盐, ≥98% (HPLC)
品質等級
化驗
≥98% (HPLC)
形狀
powder
藥物控制
regulated under CDSA - not available from Sigma-Aldrich Canada
顏色
white to beige
溶解度
0.1 M HCl: 0.25 mg/mL
DMSO: 12 mg/mL
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 2.4 mg/mL
0.1 M NaOH: insoluble
H2O: insoluble
SMILES 字串
CS(O)(=O)=O.Cc1c(C(=O)c2cccc3ccccc23)c4cccc5OC[C@@H](CN6CCOCC6)n1c45
InChI
1S/C27H26N2O3.CH4O3S/c1-18-25(27(30)22-9-4-7-19-6-2-3-8-21(19)22)23-10-5-11-24-26(23)29(18)20(17-32-24)16-28-12-14-31-15-13-28;1-5(2,3)4/h2-11,20H,12-17H2,1H3;1H3,(H,2,3,4)/t20-;/m1./s1
InChI 密鑰
FSGCSTPOPBJYSX-VEIFNGETSA-N
基因資訊
human ... CNR1(1268) , CNR2(1269)
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
A Richter et al.
European journal of pharmacology, 264(3), 371-377 (1994-11-03)
The effects of the novel high affinity cannabinoid receptor agonist (+)-WIN 55,212-2 ((R)-4,5-dihydro-2-methyl-4(4-morphoinylmethyl)-1-(1-naphthalen ylcarbonyl)-6H-pyrrolo[3,2,1-ij]quinolin-6-one) on severity of dystonia were investigated in mutant Syrian hamsters with primary generalized dystonia. Following injections of (+)-WIN 55,212-2 (1.0-5.0 mg/kg i.p.) a dose-dependent reduction of
Gaëtan Philippot et al.
Toxicological sciences : an official journal of the Society of Toxicology, 166(1), 203-212 (2018-08-31)
Acetaminophen (AAP; also known as paracetamol) is the most used and only recommended analgesic and antipyretic among pregnant women and young children. However, recent findings in both humans and rodents suggest a link between developmental exposure to AAP and adverse
Dual Role of PPAR-c in Induction and Expression of Behavioral Sensitization to Cannabinoid Receptor Agonist WIN55,212-2
Enayatfard L, et al.
Neuromolecular Medicine, 15, 523-535 (2013)
X Pan et al.
Molecular pharmacology, 49(4), 707-714 (1996-04-01)
Modulation of neuronal ion channels by the cloned rat brain CB1 cannabinoid receptor was investigated with the use of a heterologous neuronal expression system. Transient expression of the rat brain CB1 cannabinoid receptor was accomplished through microinjection of in vitro
Rational design and synthesis of an orally active indolopyridone as a novel conformationally constrained cannabinoid ligand possessing antiinflammatory properties
Wrobleski ST, et al.
Journal of Medicinal Chemistry, 46(11), 2110-2116 (2003)
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Once reconstituted, at what temperature should it be kept?
1 answer-
Helpful?
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Can WIN be dissolved in Dimethylformamide (DMF) to achieve a concentration of 10 mM?
1 answer-
The solubility of this chemical in DMF has not been officially determined. Nevertheless, according to various sources, this chemical can be solubilized in approximately 30 mg/ml of DMF.
Helpful?
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Hello, How should this product be stored (what temperature ?). Thanks in advance.
1 answer-
This product is to be stored in room temperature.
Helpful?
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Is WIN dissolvable in Dimethylformamide (DMF) in a concentration of 10 mM?
1 answer-
The solubility of this chemical in DMF has not been determined. However, various sources state this chemical can be solubilized in about 30 mg/ml of DMF.
Helpful?
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