推荐产品
生物源
bovine plasma
品質等級
產品線
BioReagent
形狀
lyophilized powder
包裝
pkg of 50 μg
技術
cell culture | mammalian: suitable
表面覆盖率
0.1 μg/cm2
溶解度
water: soluble 1.0 mL, clear, colorless
UniProt登錄號
運輸包裝
ambient
儲存溫度
2-8°C
基因資訊
bovine ... VTN(507525)
應用
Recommended as a cell culture substratum at 0.1 μg/cm2. Optimal conditions for attachment must be determined for each cell line and application.
生化／生理作用
Vitronectin binds to glycosaminoglycans, is incorporated as an inhibitor to the membrane cytolytic attack complex of the complement system, has interaction with thrombin and antithrombin III during coagulation, and may play a role in the coagulation pathway.
成分
Vitronectin is a glycoprotein present in plasma and tissues, and is one of the major cell adhesion proteins, along with fibronectin, in plasma. The N-terminal residues of vitronectin are identical to somatomedin B and are followed by an R-G-D sequence that interacts with a specific cell-surface receptor. The central domain of vitronectin is enriched with hydrophobic residues. Closer to the C-terminus, it has an arginine rich region that allows for heparin binding activity.
注意
The lyophilized product should be stored desiccated at 2-8°C. Under these conditions it is stable for at least 2 years. Aliquots should be stored at -20°C or -70°C, but repeated freezing and thawing should be avoided.
準備報告
This product is supplied as a cell culture tested lyophilized powder from buffered saline. It is recommended to use polypropylene vessels during handling, due to the strong affinity of vitronectin for hydrophilic surfaces. Reconstitution of this product can be done with 1 mL of water per vial. The stock solution should then be filter-sterilized using a 0.2μm membrane and aliquoted and frozen for long term storage.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
Stephanie L Gupton et al.
The Journal of cell biology, 198(4), 657-676 (2012-08-22)
Mena is an Ena/VASP family actin regulator with roles in cell migration, chemotaxis, cell-cell adhesion, tumor cell invasion, and metastasis. Although enriched in focal adhesions, Mena has no established function within these structures. We find that Mena forms an adhesion-regulated
Yusuke Arima et al.
Acta biomaterialia, 26, 72-81 (2015-08-27)
We examined the effect of surface chemistry on adsorption of fibronectin (Fn) and vitronectin (Vn) and subsequent cell adhesion, employing self-assembled monolayers (SAMs) of alkanethiols carrying terminal methyl (CH3), hydroxyl groups (OH), carboxylic acid (COOH), and amine (NH2). More Fn
Joseph Mathew Kalappurakkal et al.
Cell, 177(7), 1738-1756 (2019-05-21)
Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are a major class of lipid-anchored plasma membrane proteins. GPI-APs form nanoclusters generated by cortical acto-myosin activity. While our understanding of the physical principles governing this process is emerging, the molecular machinery and functional relevance of GPI-AP
商品
3D cell culture overview. Learn about 2D vs 3D cell culture, advantages of 3D cell culture, and techniques available to develop 3D cell models
3D细胞培养概述。了解2D与3D细胞培养的对比结果，3D细胞培养的优势以及可用于开发3D细胞模型的技术
培养和表征CSC群体的癌症干细胞培养基、球状体培养板和癌症干细胞标志物。
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门