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品質等級
化驗
≥98%
形狀
powder
mp
256-257 °C (lit.)
儲存溫度
2-8°C
SMILES 字串
[H][C@]12CC[C@]3([H])[C@@]4(C)CC[C@H](O)C(C)(C)[C@]4([H])CC[C@@]3(C)[C@]1(C)CC[C@@]5(CO)CC[C@@H](C(C)=C)[C@]25[H]
InChI
1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1
InChI 密鑰
FVWJYYTZTCVBKE-ROUWMTJPSA-N
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一般說明
桦木醇是一种具有羽扇豆核的三萜类化合物 ，存在于桦树的树皮中。在酸剂存在下发生重排形成同种桦木醇。
應用
桦木醇可用于桦木酸的制备， 桦木酸具有抗 HIV、抗疟和抗炎活性。
訊號詞
Warning
危險聲明
危險分類
STOT SE 2
標靶器官
Eyes,Central nervous system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
其他客户在看
Cindy Horwedel et al.
Journal of medicinal chemistry, 53(13), 4842-4848 (2010-06-10)
A novel approach to circumvent multidrug resistance is hybridization of natural products in dimers. We analyzed homodimers of two artesunic acid molecules and heterohybrids of artesunic acid and betulin in human CCRF-CEM and multidrug-resistant P-glycoprotein-overexpressing CEM/ADR5000 leukemia cells. Multidrug-resistant cells
Betulin and its derivatives. Chemistry and biological activity.
Tolstikov GA, et al.
Chemistry for Sustainable Development, 13, 1-29 (2005)
A concise semi-synthetic approach to betulinic acid from betulin.
Kim DSHL, et al.
Synthetic Communications, 27(9), 1607-1612 (1997)
Sayan Chowdhury et al.
Molecular pharmacology, 80(4), 694-703 (2011-07-14)
Toward developing antileishmanial agents with mode of action targeted to DNA topoisomerases of Leishmania donovani, we have synthesized a large number of derivatives of betulin. The compound, a natural triterpene isolated from the cork layer of Betula spp. plants exhibits
Sami Alakurtti et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 29(1), 1-13 (2006-05-24)
Betulin (lup-20(29)-ene-3beta,28-diol) is an abundant naturally occurring triterpene and it is found predominantly in bushes and trees forming the principal extractive (up to 30% of dry weight) of the bark of birch trees. Presently, there is no significant use for
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