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Merck

91228

Sigma-Aldrich

三氯乙酸

BioUltra, ≥99.5% (T)

别名:

TCA

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100 G
$146.00
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$514.00

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100 G
$146.00
1 KG
$413.00
500 G
$514.00

About This Item

线性分子式:
Cl3CCOOH
CAS号:
分子量:
163.39
Beilstein:
970119
EC 号:
MDL编号:
UNSPSC代码:
12352101
PubChem化学物质编号:
NACRES:
NA.25

$146.00


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等级

biotech. grade

蒸汽密度

<1 (vs air)

蒸汽压

1 mmHg ( 51 °C)

产品线

BioUltra

方案

≥99.5% (T)

表单

crystals
flakes

杂质

insoluble matter, passes filter test

灼烧残渣

≤0.05%

折射率

n20/D 1.62 (lit.)

pH值(酸碱度)

<1.0 (25 °C, 0.5 M in H2O)

沸点

196 °C (lit.)

mp

54-58 °C (lit.)

溶解性

H2O: 0.5 M at 20 °C, clear, colorless

密度

1.62 g/mL at 25 °C (lit.)

痕量阴离子

chloride (Cl-): ≤30 mg/kg
nitrate (NO3-): ≤20 mg/kg
phosphate (PO43-): ≤10 mg/kg
sulfate (SO42-): ≤100 mg/kg

痕量阳离子

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

SMILES字符串

OC(=O)C(Cl)(Cl)Cl

λ

0.5 M in H2O

紫外吸收

λ: 260 nm Amax: 1.60
λ: 280 nm Amax: 0.15

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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一般描述

三氯乙酸(TCA)来源于三氯乙烯(TCE)代谢。[1]它可用作酸脱钙剂。TCA可用作核染色和蛋白质沉淀的固定剂。[2]

应用

三氯乙酸(TCA)已用于:
  • 确定其在涵盖心脏规格(cardiac specification)的暴露窗口(exposure window)期间对禽类胚胎的影响[3]
  • 作为细胞固定剂[4][5][6]
  • 终止O-乙酰丝氨酸(硫醇)裂解酶(OASTL)酶促测定[6]
  • 用于沉淀酸性核糖体蛋白(RP)[7]

传统上用于沉淀蛋白质。用于通过定量沉淀测定蛋白质浓度。用作脱钙剂和显微镜样品的固定剂。

其他说明

Concentration of protein by quantitative precipitationcitation; Cytochemical demonstration of DNA with a thiazine dyecitation
通过定量沉淀浓缩蛋白质[8];用噻嗪染料对DNA进行细胞化学观察[9]

象形图

CorrosionEnvironment

警示用语:

Danger

危险声明

危险分类

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

储存分类代码

8B - Non-combustible corrosive hazardous materials

WGK

WGK 2

闪点(°F)

>235.4 °F - closed cup

闪点(°C)

> 113 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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其他客户在看

M.K. Dutt
Science and Culture, 51, 196-196 (1985)
Histophatologic Techniques (2006)
Efficacy of 5-FU or oxaliplatin monotherapy over combination therapy in colorectal cancer
Toloudi M, et al.
Journal of Cancer Therapy, 6(04), 345-345 (2015)
Extraction and Activity of O-acetylserine (thiol) lyase (OASTL) from Microalga Chlorella sorokiniana
Salbitani G and Carfagna S
Bio-protocol (2016)
CHCHD4 confers metabolic vulnerabilities to tumour cells through its control of the mitochondrial respiratory chain
Thomas L, et al.
Cancer & Metabolism, 7(1), 2-2 (2019)

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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