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一般描述
应用
NGFβ(神经生长因子β)已被用于治疗正常的人支气管上皮细胞(NHBE),以确定其在阿米洛利、NPPB和哇巴因存在下对离子转运的影响。它还可用于在细胞中与MKHS(改良的Krebs-Henseleit溶液)进行顶端培养,以确定其在延长的MKHS孵育期后的稳定性和浓度。[4]
生化/生理作用
序列
SSSHPIFHRG EFSVCDSVSV WVGDKTTATD IKGKEVMVLG EVNINNSVFK QYFFETKCRD PNPVDSGCRG IDSKHWNSYC TTTHTFVKAL TMDGKQAAWR FIRIDTACVC VLSRKAVR
外形
冻干品,无添加剂。
重悬
在打开之前将小瓶进行离心。用水进行重悬至浓度为0.1-1.0 mg/ml。不要涡旋。该溶液可在2-8℃下储存最长达1周。如需更长时间的储存,建议使用含有稳定剂(如5%海藻糖)的缓冲液进行进一步的稀释,并在分装成工作体积后冻存在-20°C至-80°C。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Over-expression of nerve growth factor-? in human cholangiocarcinoma QBC939 cells promote tumor progression.
Yue XJ, et al.
PLoS ONE, 8(4) (2013)
Nerve growth factor reduces amiloride-sensitive Na+ transport in human airway epithelial cells.
Shimko MJ, et al.
Physiological Reports, 2(7) (2014)
Li Lin et al.
Molecules (Basel, Switzerland), 24(10) (2019-05-28)
Two optical isomers, +/- gelsemine (1, 2), together with one known compound were isolated from the whole plant of G. elegans. The structures of the separated constituents were elucidated on 1D and 2D (1H-1H COSY, HMBC, HSQC) NMR spectroscopy and
Urinary nerve growth factor could be a biomarker for interstitial cystitis/painful bladder syndrome: a meta-analysis.
Qu HC, et al.
PLoS ONE, 9(9) (2014)
The effect of antenatal depression and selective serotonin reuptake inhibitor treatment on nerve growth factor signaling in human placenta.
Kaihola H, et al.
PLoS ONE, 10(1) (2015)
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