SML3208

CPYPP

≥98% (HPLC)

• 别名: 4-[3′-(2′′-chlorophenyl)-2′-propen-1′-ylidene]-1-phenyl-3,5-pyrazolidinedione
• 经验公式（希尔记法）: C₁₈H₁₃ClN₂O₂
• CAS号: 310460-39-0
• 分子量: 324.76
• MDL编号: MFCD00980987
• UNSPSC代码: 51111800
• NACRES: NA.77

属性

• 质量水平: 100
• 方案: ≥98% (HPLC)
• 表单: powder
• 颜色: orange to dark red
• 溶解性: DMSO: 2 mg/mL, clear
• 储存温度: −20°C
• SMILES字符串: Clc1c(cccc1)C=CC=C2C(=O)N(NC2=O)c3ccccc3
• InChI: 1S/C18H13ClN2O2/c19-16-12-5-4-7-13(16)8-6-11-15-17(22)20-21(18(15)23)14-9-2-1-3-10-14/h1-12H,(H,20,22)
• InChI key: VVZJFICTTKPNCK-UHFFFAOYSA-N

说明

生化/生理作用

CPYPP is a cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain. CPYPP is a DOCK2-Rac1 interaction inhibitor. It also inhibits DOCK1 and DOCK5. CPYPP potently inhibits metastatic spread of aggressive ROBO1deficient prostate cancer cells through the vasculature of transgenic Zebrafish model.

cell permeable potent and selective reversible inhibitor of DOCK2 that binds to DOCK2 DHR-2 domain

安全信息

• 储存分类代码: 11 - Combustible Solids