SML2184

Kevetrin hydrochloride

≥98% (HPLC)

• 别名: Kevetrin hydrochloride, 4-Isothioureidobutyronitrile hydrochloride, Carbamimidothioic acid 3-cyanopropyl ester hydrochloride, NSC 525990 HCl
• 经验公式（希尔记法）: C₅H₉N₃S · HCl
• CAS号: 66592-89-0
• 分子量: 179.67
• MDL號碼: MFCD22572767
• 分類程式碼代碼: 12352200
• NACRES: NA.77

属性

• 化驗: ≥98% (HPLC)
• 形狀: powder
• 儲存條件: desiccated
• 顏色: white to beige
• 溶解度: H₂O: 2 mg/mL, clear
• 儲存溫度: −20°C
• SMILES 字串: NC(SCCCC#N)=N.Cl
• InChI: 1S/C5H9N3S.ClH/c6-3-1-2-4-9-5(7)8;/h1-2,4H2,(H3,7,8);1H
• InChI 密鑰: NCXJZJFDQMKRKM-UHFFFAOYSA-N

说明

生化／生理作用

Kevetrin is an activator/stabilizer of wild type p53 tumor suppressor protein in human lung carcinoma and ovarian cancer cells that induces cell cycle arrest and apoptosis. Additionally Kevetrin down-regulates oncogenic mutant p53 in OVCAR-3 ovarian cancer cells. Kevetrin inhibits tumor growth in xenograft model of ovarian cancer.

安全信息

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable