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品質等級
化驗
≥98% (HPLC)
形狀
powder
光學活性
[α]/D +48 to +58°, c = 1 in H2O
儲存條件
desiccated
顏色
white to beige
溶解度
H2O: 20 mg/mL, clear
儲存溫度
2-8°C
SMILES 字串
[Cl-].[N+H2]1C=NC=C1[C@@H](C)c2c(c(ccc2)C)C
InChI
1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1
InChI 密鑰
VPNGEIHDPSLNMU-MERQFXBCSA-N
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生化/生理作用
盐酸右美托咪定是一种高效选择性 α2-肾上腺素能激动剂,具有镇痛和镇静功效。
盐酸右美托咪定是一种高效选择性且具有镇痛和镇静属性的 α2-肾上腺素能激动剂,是美托咪定的 (+)-异构体。盐酸右美托咪定在临床上作为一种麻醉剂,用于减轻焦虑和紧张情绪,促进松弛和镇静,而不引起呼吸抑制。
特點和優勢
这种化合物是神经科学研究的特色产品。 点击此处 ,发现更多特色神经科学产品。前往 sigma.com/discover-bsm 了解更多关于其他研究领域的生物活性小分子。
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Zheng-Tao Zhang et al.
Inflammopharmacology, 31(1), 423-438 (2022-12-20)
To explore the anti-inflammatory effect and the potential mechanism of dexmedetomidine in ARDS/ALI. C57BL/6 mice and EL-4 cells were used in this research. The ALI model was established by CLP. The level of inflammatory cytokines in the lung and blood
3-Methyladenine and dexmedetomidine reverse lipopolysaccharide-induced acute lung injury through the inhibition of inflammation and autophagy
Dengfeng Ding
Experimental and Therapeutic Medicine, 15.4 (2018)
Anna K Shoveller et al.
Journal of feline medicine and surgery, 16(12), 957-965 (2014-03-15)
Body condition scoring (BCS) provides a readily available technique that can be used by both veterinary professionals and owners to assess the body condition of cats, and diagnose overweight or underweight conditions. The objective of this study was to evaluate
Heedoo Yoo et al.
European journal of clinical pharmacology, 71(10), 1197-1207 (2015-08-04)
Dexmedetomidine is an α2-adrenoceptor agonist used for perioperative and intensive care sedation. This study develops mechanism-based population pharmacokinetic-pharmacodynamic models for the cardiovascular and central nervous system (CNS) effects of intravenously (IV) and intranasally (IN) administered dexmedetomidine in healthy subjects. Single
Jia Liao et al.
International journal of molecular sciences, 22(23) (2021-12-11)
Dexmedetomidine (DEX), a selective α2 adrenergic receptor (AR) agonist, is commonly used as a sedative drug during critical illness. In the present study, we explored a novel accelerative effect of DEX on cardiac fibroblast (CF) differentiation mediated by LPS and
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