推荐产品
product name
MitoTEMPO, ≥98% (HPLC)
品質等級
化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
protect from light
顏色
white to light brown
溶解度
H2O: 10 mg/mL, clear
儲存溫度
−20°C
應用
MitoTEMPO已被用作线粒体靶向抗氧化剂。
生化/生理作用
MitoTEMPO是一种线粒体靶向抗氧化剂,一种线粒体超氧化物的特异清除剂。 MitoTEMPO是抗氧化剂哌啶硝基氧TEMPO与亲脂阳离子三苯基鏻的组合,使MitoTEMPO能够轻松通过脂质双层膜,并在线粒体中积累数百倍。 线粒体功能障碍和氧化应激可导致多种疾病,包括心血管、肾脏、肝脏疾病、帕金森′s病和阿尔茨海默′s病。
其他說明
光敏性
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Antioxidants & redox signaling, 32(13), 929-942 (2019-06-14)
Aims: Reactive oxygen species (ROS) are highly reactive molecules generated in different subcellular sites or compartments, including endosomes via
Modulation of mitochondrial antiviral signaling by human herpesvirus 8 interferon regulatory factor 1
Journal of Virology (2016)
Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy
The Journal of Biological Chemistry (2016)
Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration
Redox Biology, 508-521 (2017)
Biochemical pharmacology, 105, 42-54 (2016-02-28)
Prolonged ingestion of a cholesterol-enriched diet induces chronic, auto-inflammatory responses resulting in significant health problems including colorectal cancer. Inflammasomes are thought to mediate intestinal homeostasis, and their dysregulation contributes to inflammatory bowel diseases and colitis-associated cancer (CAC). However, in vitro
商品
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门