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Merck
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主要文件

SCP0237

Sigma-Aldrich

PAR-1 Selective Agonist

≥95% (HPLC)

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About This Item

经验公式(希尔记法):
C31H53N9O6
分子量:
647.81
分類程式碼代碼:
12352200
NACRES:
NA.32
价格与库存信息目前不能提供

化驗

≥95% (HPLC)

形狀

lyophilized

成份

Peptide Content, ≥65%

儲存條件

protect from light

儲存溫度

−20°C

Amino Acid Sequence

Thr-Phe-Leu-Leu-Arg-NH2

應用

PAR-1 selective agonist has been used for platelet aggregation.[1]
Thr-Phe-Leu-Leu-Arg-NH2 (TFLLR-NH2) is used as a selective agonist for protease-activated receptor 1 (PAR1) which is involved in the development of cardiac remodeling and hypertrophy after myocardial injury.

生化/生理作用

Protease-activated receptor-1 (PAR-1) is a G protein-coupled receptor, that is activated through thrombin and other proteases.[2]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rac Regulates the TRAP-Induced Release of Phosphorylated-HSP27 from Human Platelets via p38 MAP Kinase but Not JNK
Uematsu K, et al.
Cellular Physiology and Biochemistry, 49(4), 1523-1538 (2018)
High-resolution crystal structure of human protease-activated receptor 1
Zhang C, et al.
Nature, 492(7429), 387-387 (2012)

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