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化驗
≥95% (HPLC)
形狀
lyophilized
成份
Peptide Content, ≥65%
儲存條件
protect from light
儲存溫度
−20°C
Amino Acid Sequence
Thr-Phe-Leu-Leu-Arg-NH2
應用
PAR-1 selective agonist has been used for platelet aggregation.[1]
Thr-Phe-Leu-Leu-Arg-NH2 (TFLLR-NH2) is used as a selective agonist for protease-activated receptor 1 (PAR1) which is involved in the development of cardiac remodeling and hypertrophy after myocardial injury.
生化/生理作用
Protease-activated receptor-1 (PAR-1) is a G protein-coupled receptor, that is activated through thrombin and other proteases.[2]
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Rac Regulates the TRAP-Induced Release of Phosphorylated-HSP27 from Human Platelets via p38 MAP Kinase but Not JNK
Uematsu K, et al.
Cellular Physiology and Biochemistry, 49(4), 1523-1538 (2018)
High-resolution crystal structure of human protease-activated receptor 1
Zhang C, et al.
Nature, 492(7429), 387-387 (2012)
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