价格与库存信息目前不能提供
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产品名称
Granulocyte Elastase Substrate human,
方案
≥95% (HPLC)
表单
lyophilized
组成
Peptide Content, ≥85%
储存条件
protect from light
储存温度
−20°C
Amino Acid Sequence
Glp-Pro-Val-pNA
一般描述
生化/生理作用
Elastase is a catalytic enzyme that catalyzes the cleavage of carboxyl groups on tiny hydrophobic amino acids including glycine, alanine, and valine. Its main function is to break down elastin.[4] Free elastase in some purulent synovial fluids plays a key role in articular cartilage breakdown. Increased elastase levels in the plasma have been seen in patients with evident rheumatoid arthritis.[3]
Elastase(s) can be assayed and differentiated using chromogenic and fluorogenic Pro-Val peptide substrates such as Glp-Pro-Val-pNA and MeOSuc-Ala-Ala-Pro-Val-4-MNA.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
K Kleesiek et al.
Rheumatology international, 6(4), 161-169 (1986-01-01)
Human granulocyte elastase (EC 3.4.21.37) is released from granulocytes in large amounts in chronic inflammatory joint diseases and is therefore of special pathogenic and diagnostic importance. In order to examine the diagnostic significance of this enzyme as a clinico-chemical parameter
Effects of Nigella (Nigella sativa L.) Seed Extract on Human Neutrophil Elastase Activity
Kacem R
Nuts and Seeds in Health and Disease Prevention, 823-829 (2011)
Evaluation of exocrine pancreatic function
Cotton SW
Contemporary Practice in Clinical Chemistry, 573-585 (2020)
Use of Extracts from Squirting Cucumber (Ecballium elaterium) Seeds in Health
Attard E
Nuts and Seeds in Health and Disease Prevention, 1079-1086 (2011)
H Moriuchi et al.
Intensive care medicine, 24(7), 709-715 (1998-08-29)
Oleic acid (OA) can produce a lung injury similar to the adult respiratory distress syndrome (ARDS). Elastase and superoxides are thought to have an effect in ARDS. However, the effect that elastase and superoxide have in OA lung injury is
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