推荐产品
生物源
mouse
品質等級
重組細胞
expressed in E. coli
化驗
≥97% (SDS-PAGE)
形狀
lyophilized powder
效力
0.4-3.0 μg/mL ED50
分子量
predicted mol wt 20 kDa
包裝
pkg of 25 μg
儲存條件
avoid repeated freeze/thaw cycles
雜質
<1 EU/μg
UniProt登錄號
儲存溫度
−20°C
基因資訊
mouse ... Shh(20423)
一般說明
Sonic hedgehog (Shh) is a morphogenic glycoprotein. The gene encoding it is localized on mouse chromosome 5.
應用
Sonic hedgehog peptide from mouse has been used for neural differentiation.
生化／生理作用
Cell signaling peptide involved in embryonic morphogenic development of several tissues including Hensen′s node, the notochord, and the neural tube.
Sonic hedgehog (Shh) has a role in fracture healing and regeneration. The protein associates with its receptor Patched (Ptc-1), de-represses Smoothened (Smo) and activates the Gli family of transcription factors. Mutations in the Shh pathway have been linked to developmental diseases and cancer.
其他說明
N-terminal peptide encoding amino acid residues 25-198.
外觀
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline, pH 7.4, containing 5% trehalose and 50 μg of bovine serum albumin per 1 μg of cytokine.
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 2
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Na Song et al.
Experimental and therapeutic medicine, 15(6), 5084-5090 (2018-05-29)
Diabetes mellitus (DM) complications affect patients and cause varying damage. Skin ulcers exhibit difficulties in wound healing, and the regulatory basis for this remains unclear. High glucose concentration (HG) was utilized to mimic DM in cultured cells. Reverse transcription-quantitative polymerase
Sanming Li et al.
Journal of cellular and molecular medicine, 22(1), 230-240 (2017-08-08)
Ectodysplasin A (Eda), a member of the tumour necrosis factor superfamily, plays an important role in ectodermal organ development. An EDA mutation underlies the most common of ectodermal dysplasias, that is X-linked hypohidrotic ectodermal dysplasia (XLHED) in humans. Even though
Abolghasem Esmaeili et al.
Avicenna journal of medical biotechnology, 6(1), 21-26 (2014-02-20)
Stem cells from Human Exfoliated Deciduous teeth (SHED) have the capability to differentiate into neural cells. Neurotrophins including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4) have neurogenesis, neurotrophic, or neuroprotective effects and are expressed
Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.
Berretta A
Scientific Reports, 6, 21896-21896 (2016)
Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog.
Marigo V
Genomics, 28(1), 44-51 (1995)
商品
Cancer stem cell media, spheroid plates and cancer stem cell markers to culture and characterize CSC populations.
培养和表征CSC群体的癌症干细胞培养基、球状体培养板和癌症干细胞标志物。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门