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物種活性
rat
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type cell culture supernatant(s)
sample type plasma
sample type serum sample(s)
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.8 ng/ml
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
rat ... Adipoq(246253)
一般說明
This ELISA antibody pair detects Rat Adiponectin (ADIPOQ/ACRP30)
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
生化／生理作用
Adiponectin, also known as AdipoQ, is a plasma protein produced by adipocytes. Downregulation of adiponectin by mutation causes insulin resistance and type 2 diabetes.[1] The expression level of adiponectin in plasma is lower in obesity.[2][3] Adiponectin interacts with other proteins produced by adipocytes and is involved in triglyceride synthesis. Adiponectin in plasma lowers the expression of adhesion molecules in vascular endothelial cells and reduces the risk of atherogenic vascular diseases.[2]
其他說明
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Association of adiponectin mutation with type 2 diabetes: a candidate gene for the insulin resistance syndrome
Kondo H, et al.
Diabetes, 51(7), 2325-2328 (2002)
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
Arita Y, et al.
Biochemical and Biophysical Research Communications, 257(1), 79-83 (1999)
Genomic structure and mutations in adipose-specific gene, adiponectin
Takahashi M, et al.
International journal of obesity (2005), 24(7), 861-868 (2000)
Jóctan Pimentel Cordeiro et al.
PloS one, 17(8), e0271592-e0271592 (2022-08-12)
There are evidence that obese-resistant animals are more physically active, due to a higher rate of lipid oxidation. Efficiency in such pathways can favor greater spontaneous physical activity and, consequently, less body fat deposition. The aim of study was characterizing
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