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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
輸入
sample type cell culture supernatant(s)
sample type serum
sample type plasma
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 6 pg/mL
standard curve range: 6.14-1500 pg/mL
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... F3(2152)
一般說明
The antibody pair provided in this kit recognizes human Coagulation Factor III/Tissue Factor.
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3.[1] TF has been shown to exist in two forms, namely membrane-bound and soluble TF.[2] The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).[3]
Tissue factor (TF), also known as coagulation factor III (F3), is encoded by the gene mapped to human chromosome 1p21.3.[1] TF has been shown to exist in two forms, namely membrane-bound and soluble TF.[2] The encoded protein contains an extracellular domain (ED), a single transmembrane domain (TD) and short cytoplasmic domain (CD).[3]
應用
For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)
生化/生理作用
Tissue factor (TF) interacts with the zymogen factor VII (VII) and its activated form VIIa, and initiates blood coagulation protease cascade.[2][4] The encoded protein is involved in the pathogenesis of cardiovascular diseases, such as hypertension, atherosclerosis, acute coronary syndrome and restenosis. Thus, it is considered to be a potential therapeutic target for cardiovascular diseases.[2]
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Gordana Kocic et al.
Cancers, 12(10) (2020-10-18)
Balkan endemic nephropathy (BEN) is a chronic tubulointerstitial disease frequently accompanied by urothelial carcinoma (UC). In light of the increased UC incidence and the markers observed in BEN patients with developed UC, the aim of the current case-control study is
Christoph Schliemann et al.
Cancers, 12(6) (2020-06-11)
Aminopeptidase N (CD13) is present on tumor vasculature cells and some tumor cells. Truncated tissue factor (tTF) with a C-terminal NGR-peptide (tTF-NGR) binds to CD13 and causes tumor vascular thrombosis with infarction. We treated 17 patients with advanced cancer beyond
Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.
Bromberg M E, et al.
Thrombosis and Haemostasis, 82(01), 88-92 (1999)
Alberto Centeno et al.
Journal of investigative surgery : the official journal of the Academy of Surgical Research, 33(4), 339-349 (2018-11-01)
Background: Excessive blood loss is a relevant complication of partial liver resection. Topical hemostatic agents have proven useful to improve the control of the bleeding in this among other surgical indications. Until now all of these products have been based
Bin Jiang et al.
Biotechnology and bioengineering, 114(10), 2371-2378 (2017-05-26)
The clinical translation of cell-based therapeutics often requires highly sensitive, non-invasive imaging tools to assess cell function and distribution in vivo. The objective of this research was to determine whether human Sodium-Iodide Symporter (hNIS) ectopic expression in endothelial cells (ECs)
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