推荐产品
生物源
rabbit
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
物種活性
human, mouse
技術
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... IL17A(3605)
一般說明
IL-17A(白介素17a)是Th17(辅助T细胞)的促炎细胞因子。它定位于染色体6p12。
免疫原
来自人IL-17A中心附近的19个氨基酸肽。
生化/生理作用
IL-17A(白介素17A)在自身免疫性疾病(如多发性硬化症和类风湿关节炎)的发病机理中起主要作用。它在过敏性鼻炎(AR)中也起着致病作用。它有助于气道上皮细胞中几种趋化因子和细胞因子的形成。
聯結
可以使用阻断肽SBP4887阻断该抗体的作用。
外觀
溶剂为含有0.02%叠氮化钠的磷酸盐缓冲盐水
免責聲明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 2
閃點(°F)
Not applicable
閃點(°C)
Not applicable
IL-17A and Th17 cells in lung inflammation: an update on the role of Th17 cell differentiation and IL-17R signaling in host defense against infection
Clinical & Developmental Immunology (2013)
Scientific reports, 13(1), 5041-5041 (2023-03-29)
Infantile skin problems not only cause temporary pain and discomfort, but also have a long-term impact on health. Hence, the purpose of this cross-sectional study was to clarify the relationship between inflammatory cytokines and Malassezia fungal facial skin problems in
Foxp3 inhibits RORgammat-mediated IL-17A mRNA transcription through direct interaction with RORgammat
The Journal of Biological Chemistry, 283(25), 17003-17008 (2008)
Association between polymorphisms in cytokine genes IL-17A and IL-17F and development of allergic rhinitis and comorbid asthma in Chinese subjects
Human immunology, 73(6), 647-653 (2012)
Journal of neuroimmunology, 377, 578068-578068 (2023-03-23)
Neuropathic pain seriously affects people's life, but its mechanism is not clear. Interleukin-17 (IL-17) is a proinflammation cytokine and involved in pain regulation. Our previous study found that IL-17 markedly enhanced the excitatory activity of spinal dorsal neurons in mice
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