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About This Item
经验公式（希尔记法）:
C5H7NO2
CAS号:
分子量:
113.11
MDL號碼:
分類程式碼代碼:
12352209
eCl@ss:
32160406
PubChem物質ID:
NACRES:
NA.26
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品質等級
化驗
≥98% (TLC)
形狀
powder
顏色
white
應用
cell analysis
儲存溫度
−20°C
SMILES 字串
NC(CC#C)C(O)=O
InChI
1S/C5H7NO2/c1-2-3-4(6)5(7)8/h1,4H,3,6H2,(H,7,8)
InChI 密鑰
DGYHPLMPMRKMPD-UHFFFAOYSA-N
應用
- 代谢标记策略提高了光热和光动力协同治疗细菌感染伤口的抗菌效率：该研究表明，在光热和光动力疗法中使用ᴅʟ-丙炔甘氨酸的代谢标记策略可提高抗菌效率，从而治疗细菌感染的伤口（Li et al., 2022）。
- 肽聚糖与近红外-II 染料的代谢标记可实现肠道微生物群的体内成像。：该研究利用ᴅʟ-丙炔基甘氨酸进行代谢标记，实现了体内肠道微生物群的近红外II成像，为微生物组研究提供了新的见解（Wang et al., 2020）。
- 硫化氢上调大鼠胃黏膜碳酸氢钠共转运体1、三叶因子1和三叶因子2的mRNA表达。：研究ᴅʟ-丙炔基甘氨酸在上调胃黏膜特定 mRNA 表达中的作用，对胃肠道研究具有重要意义（Cheraghi et al., 2016）。
生化／生理作用
DL-丙炔甘氨酸（PAG）是胱硫醚γ-裂解酶（GCL）的不可逆抑制剂，该酶是一种参与谷胱甘肽合成 和调节同型半胱氨酸浓度并介导半胱氨酸合成的代谢转硫途径的关键酶。利用PAG治疗动物疾病模型显示其可减轻破坏硫化氢（H2S）形成或作用的疾病的相关症状。
訊號詞
Warning
危險聲明
危險分類
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
標靶器官
Respiratory system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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