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Merck
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文件

P7762

Sigma-Aldrich

聚L -精氨酸 盐酸盐

mol wt 15,000-70,000

别名:

L-Arginine homopolymer hydrochloride

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About This Item

CAS号:
26982-20-7
MDL號碼:
MFCD00166393
分類程式碼代碼:
12352209
PubChem物質ID:
24898874
NACRES:
NA.26

形狀

powder

分子量

15,000-70,000

顏色

white to off-white

應用

cell analysis

儲存溫度

−20°C

SMILES 字串

Cl.NC(CCCNC(N)=N)C(O)=O

InChI

1S/C18H38N12O4.ClH/c19-10(4-1-7-26-16(20)21)13(31)29-11(5-2-8-27-17(22)23)14(32)30-12(15(33)34)6-3-9-28-18(24)25;/h10-12H,1-9,19H2,(H,29,31)(H,30,32)(H,33,34)(H4,20,21,26)(H4,22,23,27)(H4,24,25,28);1H/t10-,11-,12-;/m0./s1

InChI 密鑰

PQEISBBDIRAKGR-LFELFHSZSA-N

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相关类别

一般說明

聚-L-精氨酸盐酸盐(PLA)是一种同型多聚氨基酸。聚L精氨酸盐酸盐相比聚-L-赖氨酸更能增强膜通透性。它可用作药物载体、神经保护剂及用于抗癌免疫制剂。PLA与多肽疫苗混用可促进抗原呈递细胞(APC)介导的T细胞生成并激发免疫兴奋作用。

應用

聚-L-精氨酸盐酸盐已用于：
  • 与isRNA9.2s形成复合物刺激中性粒细胞
  • 在核糖体RNA转染人单核细胞THP-1中使用
  • 包裹海藻酸微囊球

品質

含有3%或更低的鸟氨酸残基。

分析報告

分子量基于前体聚-L-鸟氨酸的粘度。 也由MALLS所测定的。

其他說明

有关聚氨基酸的其他技术信息，请访问 聚氨基酸常见问题解答资源。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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The Journal of Biological Chemistry, 287(23), 19409-19417 (2012)
Antibacterial activity of poly-l-arginine under different conditions
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