Inhibiting calcineurin activity under physiologic tonicity elevates anabolic but suppresses catabolic chondrocyte markers
van der Windt AE, et al.
Arthritis and Rheumatism, 64(6), 1929-1939 (2012)
Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Galpha12 or constitutively active RhoA
Wang J and Stern PH
Journal of Cellular Biochemistry, 111(6), 1531-1536 (2010)
Structure (London, England : 1993), 27(10), 1485-1496 (2019-08-14)
ASPP (apoptosis-stimulating proteins of p53) proteins bind PP-1c (protein phosphatase 1) and regulate p53 impacting cancer cell growth and apoptosis. Here we determine the crystal structure of the oncogenic ASPP protein, iASPP, bound to PP-1c. The structure reveals a 1:1
International journal of nanomedicine, 8, 1935-1946 (2013-06-06)
Genetically modified mesenchymal stem cells (MSCs) have great potential in the application of regenerative medicine and molecular therapy. In the present manuscript, we introduce a nanopolymer, polyethylenimine600-β-cyclodextrin (PEI600-β-CyD), as an efficient polyplex-forming plasmid delivery agent with low toxicity and ideal
IgA1 complexes containing deglycosylated IgA1, IgG autoantibodies, and a soluble form of the IgA receptor (sCD89), are hallmarks of IgA nephropathy (IgAN). Food antigens, notably gluten, are associated with increased mucosal response and IgAN onset, but their implication in the
