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Merck
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P3292

Sigma-Aldrich

胰脂肪酶 来源于猪胰腺

powder, suitable for cell culture, 4 × USP specifications

别名:

胰液素 来源于猪胰腺

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$64.10
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$182.00

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25 G
$64.10
100 G
$182.00

About This Item

CAS号:
8049-47-6
EC 号:
232-468-9
MDL编号:
MFCD00131789
UNSPSC代码:
12352204
NACRES:
NA.75

$64.10

请联系客服了解存货情况
获取大包装报价

生物来源

Porcine pancreas

Agency

USP (specifications)

表单

powder

比活

4 × USP specifications

包含

lactose or sucrose as extender (The sucrose used might contain up to 3.25% starch.)

技术

cell culture | mammalian: suitable

运输

ambient

储存温度

−20°C

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相关类别

应用

来自猪胰腺的胰酶可用于评估脂肪酶补充疗法治疗脂肪泻，研究慢性胰腺炎失代偿期患者的胰腺糖尿病治疗方案，并安全地、有效地从动脉移植物中去除福尔马林固定的组织而不引起结构损坏或纤维完整性损失。

生化/生理作用

胰酶由猪胰腺的外分泌细胞产生，含有胰蛋白酶、淀粉酶和脂肪酶、核糖核酸酶和蛋白酶等酶组份。 这种酶的组合使其能够水解蛋白质、淀粉和脂肪。 在 40°C 水中，胰酶在 5 分钟内将不少于其重量 25 倍的马铃薯淀粉转化为可溶性碳水化合物，在 pH7.5，40℃ 下，胰酶在 60 分钟内消化不少于重量 25 倍的酪蛋白，在 pH9.0，37℃ 下，每毫克胰酶每分钟将从橄榄油中释放不低于微当量的酸。

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象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Danger

危险分类

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 1

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000365058
0000339094
0000309578
0000365058
0000309578

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Questions

1–2 of 2 Questions  

  1. Bonjour, Nous avons besoin de la valeur exacte (chiffrée) de l'activité protease selon monographie USP Pancreatin - Assay for protease activity. Est ce une information disponible sur le CoA du produit ? Ou que nous pouvons obtenir ? Merci d'avance,

    1 answer

    1. The specific activity of the pancreatin is specified in multiples of the minimum USP standard (USP 24, p. 1254). The USP defines a minimum specification of 1X Pancreatin as follows:
      25 USP protease units per mg.
      25 USP amylase units per mg.
      2 USP lipase units per mg.

      For the 4 × USP the above values are multiplied by four. The product Certificate of Analysis confirms that this specification has been met, but no activity values are reported. The USP defines units as:
      One USP Unit of amylase activity is contained in the amount of pancreatin that decomposes starch at an initial rate such that 0.16 µ Eq of glycosidic linkage is hydrolyzed per minute under the conditions of the Assay for amylase activity.

      One USP Unit of lipase activity is contained in the amount of pancreatin that liberates 1.0 µ Eq of acid per minute at a pH of 9.0 and 37° under the conditions of the Assay for lipase activity.

      One USP Unit of protease activity is contained in the amount of pancreatin that under the conditions of the Assay for protease activity hydrolyzes casein at an initial rate such that there is liberated per minute an amount of peptides not precipitated by trichloroacetic acid that gives the same absorbance at 280 nm as 15 nmol of tyrosine.
      The specific monograph may not be shared due to copyright laws. Please refer to the USP to review the published monograph.

      Helpful?

  2. What are the USP/mg for pancreatin (P3292)?

    1 answer

    1. This product meets 4X the minimum USP specifications. According to the USP monograph for Pancreatin, the 1X minimum specification is 25 USP units amylase, 2 USP units lipase, and 25 USP units protease per milligram. The calculated protease activity for the 4X preparation then, would be at least 100 units per milligram. This is a calculated value based on the USP monograph and are not reported separately on the Certificate of Analysis.

      Helpful?

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