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Merck

P0763

Sigma-Aldrich

1,2-二棕榈酰-sn-甘油-3-磷酰胆碱

semisynthetic, ≥99%

别名:

PC, (7R)-4-羟基-N,N,N-三甲基-10-氧代-7-[(1-氧代十六烷基)氧基]- 3,5,9-三氧杂-4-磷杂二十五烷-1-铵4-氧化物, 内盐, 1,2-二十六酰--甘油基-3-磷酸胆碱, 1,2-二棕榈酰-sn-甘油-3-磷酰胆碱, 1,2-二棕榈酰- L -卵磷脂, 1,2-双十六酰基-sn-甘油-3-磷酰胆碱, L-α-磷脂酰胆碱,二棕榈酰, L-β,γ-二棕榈酰-α-卵磷脂, PC(16:0/16:0), 二棕榈酰磷脂酰胆碱

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About This Item

经验公式(希尔记法):
C40H80NO8P
CAS号:
分子量:
734.04
EC號碼:
MDL號碼:
分類程式碼代碼:
12352211
PubChem物質ID:
NACRES:
NA.25

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生物源

semisynthetic

品質等級

化驗

≥99%

形狀

powder

官能基

phospholipid

脂質類型

phosphoglycerides

運輸包裝

ambient

儲存溫度

−20°C

SMILES 字串

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)=O

InChI

1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

InChI 密鑰

KILNVBDSWZSGLL-KXQOOQHDSA-N

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應用


  • η(6)-对伞花烃钌(II)配合物对模拟癌症和健康细胞膜的Langmuir单分子膜的影响与其毒性无关。:该研究探讨了η(6)-对伞花烃钌(II)复合物对模拟癌症和健康细胞膜的Langmuir单分子膜(包括1,2-二棕榈酰-sn-甘油-3-磷酸胆碱(DPPC))的影响,揭示了膜相互作用和细胞毒性机制(Wrobel et al., 2024)。

  • L-苯丙氨酸与混合脂膜中羰基的相互作用。:该研究探讨了L-苯丙氨酸与混合脂膜(含有 DPPC)中羰基的相互作用,以了解氨基酸在膜动力学和稳定性中的作用(Brandan et al., 2024)。

  • 存在脂质筏时布洛芬药物在模型膜中的空间排列。:该研究调查了以DPPC为成分时,布洛芬在含有脂质筏的模型膜中的空间排列,揭示了药物与膜的相互作用以及脂质筏在药物输送中的作用(Kashnik et al., 2024)。

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Johannes Thoma et al.
Chemical communications (Cambridge, England), 48(70), 8811-8813 (2012-07-28)
We present a model system to demonstrate that the positioning of biomolecules (membrane proteins) in a nonnative, complex thin film environment can be regulated by the phase behavior of film components. Partial separation between an amphiphilic polymer and a lipid
Edyta Paszko et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 48(1-2), 202-210 (2012-11-20)
Photodynamic therapy (PDT) is based on the delivery of photocytotoxic agents to a target tissue, followed by irradiation. In order to increase the efficiency of PDT in oesophageal cancer therapy, polyethylene glycol (PEG)-grafted, transferrin (Tf)-conjugated liposome formulations of 5,10,15,20-tetra(m-hydroxyphenyl)chlorin (Foscan)
Fernando R Moya et al.
Pediatrics, 115(4), 1018-1029 (2005-04-05)
Evidence suggests that synthetic surfactants consisting solely of phospholipids can be improved through the addition of peptides, such as sinapultide, that mimic the action of human surfactant protein-B (SP-B). A synthetic surfactant containing a mimic of SP-B may also reduce
John M Franck et al.
Journal of the American Chemical Society, 135(11), 4175-4178 (2013-01-26)
The translational hydration dynamics within 0.5-1.5 nm of the surface of a DPPC liposome, a model biomacromolecular surface, is analyzed by the recently developed Overhauser dynamic nuclear polarization (ODNP) technique. We find that dramatic changes to the bulk solvent cause
Julien Perino et al.
Antiviral research, 89(1), 89-97 (2010-11-26)
Vaccinia virus (VACV) was used as a surrogate of Variola virus (genus Orthopoxvirus), the causative agent of smallpox, to study orthopoxvirus infection via the respiratory airway. Lung surfactant, a physiological barrier to infection encountered by the virus, is predominantly composed

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