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Merck

N7160

Sigma-Aldrich

NAD-ADH Reagent Multiple Test Vial

for alcohol determination

别名:

Ethanol assay reagent

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10 X 16 ML
$579.00

$579.00


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10 X 16 ML
$579.00

About This Item

UNSPSC代码:
41106305
NACRES:
NA.51

$579.00


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获取大包装报价

质量水平

表单

powder

储存温度

−20°C

应用

NAD-ADH Reagent Multiple Test Vial has been used to determine the alcohol content in blood.[1] It has also been used to detect ethanol levels in mice.[2]

生化/生理作用

Alcohol dehydrogenase (ADH) catalyzes the oxidation of alcohol to acetaldehyde[3] with the simultaneous reduction of nicotinamide adenine dinucleotide (NAD) to NADH.[4] The consequent increase in absorbance at 340 nm is directly proportional to alcohol concentration in the sample.

其他说明

Vial contains ≥10 μmol of nicotinamide adenine dinucleotide (NAD) and ≥800 units of yeast alchohol dehydrogenase (ADH), buffer salts, and stabilizers.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

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Denys V Volgin
Neuroscience letters, 439(2), 182-186 (2008-06-03)
Prenatal alcohol exposure (AE) is associated with lasting abnormalities of sleep and motor development, but the underlying mechanisms are unknown. We hypothesized that AE alters development of GABAergic signaling in the hypothalamic regions important for the control of sleep and
A rapid enzymatic method for estimating ethanol in body fluids.
D Jones et al.
Clinical chemistry, 16(5), 402-407 (1970-05-01)
Ana M Romero et al.
Neurotoxicity research, 29(1), 69-79 (2015-08-13)
Chronic alcohol consumption may cause neurodevelopmental and neurodegenerative disorders. Alcohol neurotoxicity is associated with the production of acetaldehyde and reactive oxygen species that induce oxidative DNA damage. However, the molecular mechanisms by which ethanol disturbs the DNA damage response (DDR)
Isabelle Larosche et al.
The Journal of pharmacology and experimental therapeutics, 332(3), 886-897 (2009-12-18)
Alcohol consumption increases reactive oxygen species (ROS) formation, which can damage mitochondrial DNA (mtDNA) and alter mitochondrial function. To test whether manganese superoxide dismutase (MnSOD) modulates acute alcohol-induced mitochondrial alterations, transgenic MnSOD-overexpressing (MnSOD(+++)) mice, heterozygous knockout (MnSOD(+/-)) mice, and wild-type
Duygu Dee Harrison-Findik et al.
The Journal of biological chemistry, 281(32), 22974-22982 (2006-06-02)
Patients with alcoholic liver disease frequently exhibit iron overload in association with increased hepatic fibrosis. Even moderate alcohol consumption elevates body iron stores; however, the underlying molecular mechanisms are unknown. Hepcidin, a circulatory peptide synthesized in the liver, is a

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