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Merck

M3781

Sigma-Aldrich

6α-Methylprednisolone 21-hemisuccinate sodium salt

lyophilized powder

别名:

6α-Methylprednisolone sodium succinate, MPSL, 6α-Methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione 21-hemisuccinate

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25 MG
$119.00
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$621.00
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25 MG
$119.00
250 MG
$621.00
1 G
$1,960.00

About This Item

线性分子式:
C26H33O8Na
CAS号:
分子量:
496.53
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77

$119.00


请联系客服了解存货情况
新价格,新优惠!

获取大包装报价

生物来源

synthetic

无菌性

non-sterile

方案

≥98.00% (TLC)

表单

lyophilized powder

技术

toxicology assay: suitable

溶解性

water: 50 mg/mL, clear, colorless to faintly yellow

运输

ambient

储存温度

room temp

SMILES字符串

[Na+].C[C@H]1CC2C3CC[C@](O)(C(=O)COC(=O)CCC([O-])=O)[C@@]3(C)C[C@H](O)C2[C@@]4(C)C=CC(=O)C=C14

InChI

1S/C26H34O8.Na/c1-14-10-16-17-7-9-26(33,20(29)13-34-22(32)5-4-21(30)31)25(17,3)12-19(28)23(16)24(2)8-6-15(27)11-18(14)24;/h6,8,11,14,16-17,19,23,28,33H,4-5,7,9-10,12-13H2,1-3H3,(H,30,31);/q;+1/p-1/t14-,16-,17-,19-,23+,24-,25-,26-;/m0./s1

InChI key

FQISKWAFAHGMGT-SGJOWKDISA-M

基因信息

human ... NR3C1(2908)

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相关类别

应用

6α-methylprednisolone 21-hemisuccinate sodium salt has been used to investigate glucocorticoid-induced osteonecrosis under hypoxic conditions in the MC3T3-E1 osteoblast cell line using a cell cytotoxicity assay, flow cytometry and western blotting.[1]

生化/生理作用

Glucocorticoid with slightly longer half-life than that of prednisolone.

外形

Lyophilized containing ~5% phosphate buffer salts.

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Carc. 2 - Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Dapsone hypersensitivity syndrome complicated by Scedosporium apiospermum pneumonia in an immunocompetent patient.
L Ceccarelli et al.
Infection, 40(4), 459-462 (2011-11-30)
Julie M Jones et al.
The Journal of the American Osteopathic Association, 112(2), 90-92 (2012-02-15)
Hypocomplementemic urticarial vasculitis syndrome (HUVS) is a type III hypersensitivity reaction characterized by urticaria with persistent acquired hypocomplementemia. Although HUVS is uncommon, it is important for physicians to be familiar with this disease, as the initial presentation is often life-threatening
Rina Ulmansky et al.
Journal of controlled release : official journal of the Controlled Release Society, 160(2), 299-305 (2012-01-10)
We have previously shown that intravenous (i.v.) treatment with sterically stabilized nano-liposomes (NSSL) actively remote-loaded with the glucocorticoid (GC) methylprednisolone hemisuccinate (NSSL-MPS) or betamethasone hemisuccinate (NSSL-BMS) significantly decreased severity of adjuvant arthritis in Lewis rats (a model of human rheumatoid
[The issue of methylprednisolone sodium succinate dosage for use].
Yu-cai Zhang et al.
Zhonghua er ke za zhi = Chinese journal of pediatrics, 49(5), 389-390 (2011-06-01)
Anna Péterfi et al.
Ideggyogyaszati szemle, 64(1-2), 24-28 (2011-03-25)
Both men and women are affected by the rare disease called Tolosa-Hunt syndrome. We don't know exactly what causes it to evolve. It is usually put into the categories of either idiopathic inflammation or pseudotumor. Its pathological feature is a

Questions

  1. How long is product M3781 good for once it is reconstituted in water?

    1 answer
    1. There is no available information on the duration for which the product remains viable once reconstituted, as it was not tested for this purpose.

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