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Merck
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Key Documents

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M3184

Sigma-Aldrich

MG 624

≥98%

别名:

N,N,N-Triethyl-2-(4-trans-stilbenoxy)ethylammonium iodide

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About This Item

经验公式（希尔记法）:
C22H30INO
CAS号:
77257-42-2
分子量:
451.38
MDL號碼:
MFCD00865233
分類程式碼代碼:
12352200
PubChem物質ID:
24278547
NACRES:
NA.77

品質等級

100

化驗

≥98%

溶解度

DMSO: ≤22 mg/mL
H2O: insoluble

儲存溫度

2-8°C

SMILES 字串

[I-].CC[N+](CC)(CC)CCOc1ccc(cc1)\C=C\c2ccccc2

InChI

1S/C22H30NO.HI/c1-4-23(5-2,6-3)18-19-24-22-16-14-21(15-17-22)13-12-20-10-8-7-9-11-20;/h7-17H,4-6,18-19H2,1-3H3;1H/q+1;/p-1/b13-12+;

InChI 密鑰

RDTKUZXIHMTSJO-UEIGIMKUSA-M

基因資訊

human ... CHRNA7(1139)

生化／生理作用

Nicotinic acetylcholine receptor antagonist; selectively inhibits neuronal nicotinic α-bungarotoxin sensitive receptors that contain the α7 subunit.

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Glenn W Vicary et al.
Respiratory research, 18(1), 115-115 (2017-06-04)
Tobacco-related chronic lung diseases are characterized by alterations in lung architecture leading to decreased lung function. Knowledge of the exact mechanisms involved in tobacco-induced tissue remodeling and inflammation remains incomplete. We hypothesize that nicotine stimulates the expression of extracellular matrix
C Gotti et al.
British journal of pharmacology, 124(6), 1197-1206 (1998-08-28)
1. Starting from the structure of an old 4-oxystilbene derivate with ganglioplegic activity (MG624), we synthesized two further derivates (F2 and F3) and two stereoisomers of F3 (F3A and F3B), and studied their selective effect on neuronal nicotinic acetylcholine receptor

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