M217

Monoclonal Anti-Nicotinic Acetylcholine Receptor (α₁, α₃, α₅ Subunits) antibody produced in rat

clone mAb 35, purified immunoglobulin, buffered aqueous solution

• 别名: Anti-ACHR
• MDL號碼: MFCD00677279
• 分類程式碼代碼: 12352203
• NACRES: NA.43

属性

• 生物源: rat
• 共軛: unconjugated
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: mAb 35, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human, chicken, eel
• 應無反應活性: Xenopus
• 技術: immunohistochemistry (frozen sections): 1:3,000
• 同型: IgG1
• UniProt登錄號: CHRNA1
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... CHRNA1(1134) , CHRNA3(1136) , CHRNA5(1138)

说明

特異性

Binds to the main immunogenic region on the extracellular surface of the α₁ subunit of muscle AChR′s and to homologous regions on α₃ and α₅ subunits of neuronal AChR′s. The epitope is located on the extracellular surface of the α₁ subunit of the muscle nicotinic acetylcholine receptor. The antibody binds to denatured chick α₅ AChR, but does not bind well to denatured α₃, α₄, α₇, α_8, and β₂. It may also bind β₃ due to homology of main immunogenic region. May be used to localize and detect the α₁, α₃ and α₅ subunits of the nicotinic acetylcholine receptor (AChR).

免疫原

nicotinic acetylcholine receptor from the electric eel Electrophorus.

外觀

Solution in 20 mM Na₃PO₄, pH 7.2, containing 150 mM NaCl and 0.05 % sodium azide.

法律資訊

Sold with permission of the Salk Institute

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)