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Merck

L5918

Sigma-Aldrich

洛莫司汀

≥98%

别名:

1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea

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About This Item

经验公式(希尔记法):
C9H16ClN3O2
CAS号:
分子量:
233.70
EC號碼:
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:
NACRES:
NA.25
价格与库存信息目前不能提供

品質等級

化驗

≥98%

儲存溫度

−20°C

SMILES 字串

ClCCN(N=O)C(=O)NC1CCCCC1

InChI

1S/C9H16ClN3O2/c10-6-7-13(12-15)9(14)11-8-4-2-1-3-5-8/h8H,1-7H2,(H,11,14)

InChI 密鑰

GQYIWUVLTXOXAJ-UHFFFAOYSA-N

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生化/生理作用

Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells.

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Carc. 1B

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

個人防護裝備

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C F Saba et al.
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Treatment of feline vaccine-associated sarcoma (VAS) is challenging, in part due to the high likelihood of tumour recurrence despite aggressive local therapy. Lomustine is potentially an attractive agent to add to the current treatment armamentarium. In this de-escalating phase I/II
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The Journal of veterinary medical science, 74(11), 1517-1521 (2012-07-13)
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A randomized, phase III, placebo-controlled, partially blinded clinical trial (REGAL [Recent in in Glioblastoma Alone and With Lomustine]) was conducted to determine the efficacy of cediranib, an oral pan-vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitor, either as monotherapy
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