It is recommended that I7908 be reconstituted in 50mm Phosphate buffer, pH 7 containing 0.1 % BSA or HSA. Please see the link below the access the product datasheet for additional information:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/427/488/i7908dat.pdf
推荐产品
产品名称
白细胞介素-2 人, recombinant, expressed in Pichia pastoris, suitable for cell culture
生物来源
human
质量水平
重组
expressed in Pichia pastoris
方案
≥98% (SDS-PAGE and HPLC)
表单
lyophilized powder
分子量
predicted mol wt ~15 kDa
包装
pkg of 10KU
技术
cell culture | mammalian: suitable
杂质
endotoxin, tested
UniProt登记号
运输
dry ice
储存温度
−20°C
基因信息
human ... IL2(3558)
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相关类别
应用
人白介素2已用于评估肿瘤坏死因子受体1（TNFR1）的变化。它也已用于Tregs上的TNFR2表达。[1]
生化/生理作用
白细胞介素-2（IL-2）是由某些T淋巴细胞亚群产生的免疫调节因子。该淋巴因子能够促进活化T细胞和相关细胞类型的长期生长。IL-2在NK细胞的激活和增殖、诱导γ-干扰素和B细胞生长因子分泌中发挥作用，并且能够调节IL-2受体的表达。
外形
从50 mM磷酸钠缓冲盐水（pH值7.0）中的0.2 μm过滤溶液中冻干，每0.1 mL细胞因子含有0.1%人血清白蛋白。
分析说明
在使用IL-2依赖性鼠细胞毒性T细胞系CTLL-2的细胞增殖测定中测试生物活性。
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
其他客户在看
Meera V Singh et al.
Journal of leukocyte biology, 109(4), 807-820 (2020-07-15)
In addition to their role in hemostasis, platelets store numerous immunoregulatory molecules such as CD40L, TGFβ, β2-microglobulin, and IL-1β and release them upon activation. Previous studies indicate that activated platelets form transient complexes with monocytes, especially in HIV infected individuals
Nader Bayda et al.
Cancers, 13(4) (2021-02-10)
The Epstein-Barr virus (EBV) is associated with angioimmunoblastic T cell lymphoma (AITL) in more than 80% of cases. Few studies have focused on this association and it is not clear now what role the virus plays in this pathology. We
TNFR1 and TNFR2 expression and induction on human Treg cells from type 1 diabetic subjects
Heinrich M, et al.
Antibodies, 4(1), 34-47 (2015)
Racha Bahri et al.
Cancers, 14(12) (2022-06-25)
The Epstein-Barr virus (EBV) is associated with angioimmunoblastic T cell lymphoma (AITL), a peripheral T lymphoma of poor prognosis in at least 90% of cases. The role of EBV in this pathology is unknown. Using next-generation sequencing, we sequenced the
The main function of IL-2 is to promote the development of T regulatory cells
Malek, Th, et al.
Journal of Leukocyte Biology, 74(6) (2003)
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Tenemos IL-2 expresado en Pichia Pastoris desde hace un tiempo con esta referencia (I7908) sin reconstituir. Hemos perdido el data sheet y no sabemos en qué solución debemos reconstituirlo. Contacte conmigo para resolver nuestra duda.
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