推荐产品
生物源
synthetic (organic)
化驗
≥98%
形狀
powder
mp
259-262 °C (lit.)
溶解度
water: 50 mg/mL, clear to hazy, colorless to light yellow
儲存溫度
−20°C
SMILES 字串
CN(C)c1ncnc2[nH]cnc12
InChI
1S/C7H9N5/c1-12(2)7-5-6(9-3-8-5)10-4-11-7/h3-4H,1-2H3,(H,8,9,10,11)
InChI 密鑰
BVIAOQMSVZHOJM-UHFFFAOYSA-N
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一般說明
6-二甲氨基嘌呤(6-DMAP)是一种嘌呤类代谢物，含有2个缩合杂环及与腺嘌呤的嘌呤氨基（环外氨基）连接的2个甲基。
應用
6-二甲氨基嘌呤已用于：
- 作为GR-1 aa培养基（牛培养基）补充剂，用于牛卵母细胞的孤雌激活，以研究其对胚胎发育的影响
- 核移植胚胎生产中的激活步骤
- 作为HCR2aa培养基补充剂，用于激活通过异种体细胞核移植(iSCNT)技术获得的异种胚胎
生化／生理作用
6-二甲氨基嘌呤(6-DMAP)是一种蛋白激酶和细胞周期蛋白依赖性激酶抑制剂。它是一种次生代谢产物，介导RNA修饰。6-DMAP是一种强效的细胞质分裂抑制剂，用于孤雌生殖和减数分裂研究。它也可用于促进哺乳动物卵母细胞的前核形成。根据飞秒荧光上转换光谱技术，6-DMAP是一种双荧光(dual fluorescence)分子。
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
個人防護裝備
Eyeshields, Gloves, type N95 (US)
其他客户在看
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Genetic engineering can expand the utility of pigs for modeling human diseases, and for developing advanced therapeutic approaches. However, the inefficient production of transgenic pigs represents a technological bottleneck. Here, we assessed the hyperactive Sleeping Beauty (SB100X) transposon system for
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Postovulatory ageing of mammalian oocytes occurs between their ovulation and fertilization and has been shown to decrease their developmental capabilities. Aged oocytes display numerous abnormalities, including altered Ca2+ signalling. Fertilization-induced Ca2+ oscillations are essential for activation of the embryonic development
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