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Merck

C9426

Sigma-Aldrich

CHAPS水合物

BioReagent, suitable for electrophoresis, ≥98% (HPLC)

别名:

3-[3-(胆酰胺丙基)二甲氨基]丙磺酸 水合物, CHAPS

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1 G
$121.00
5 G
$451.00

About This Item

经验公式(希尔记法):
C32H58N2O7S · xH2O
分子量:
614.88 (anhydrous basis)
MDL编号:
UNSPSC代码:
12161902
PubChem化学物质编号:
NACRES:
NB.22

$121.00


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描述

zwitterionic

产品线

BioReagent

方案

≥98% (HPLC)

表单

powder

分子量

614.88 g/mol (anhydrous basis)

技术

electrophoresis: suitable
protein quantification: suitable

杂质

<0.04% DMF

mp

157 °C (dec.) (lit.)

溶解性

water: 50 mg/mL, clear, colorless

适用性

suitable for electrophoresis

储存温度

room temp

SMILES字符串

O.C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C32H58N2O7S.H2O/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36;/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41);1H2/t21-,22+,23-,24-,25+,26+,27-,28+,30+,31+,32-;/m1./s1

InChI key

SJCUTFKCLFLIFE-JWTJKVBLSA-N

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一般描述

CHAPS是一种非变性两性离子磺基甜菜碱洗涤剂。它温和,可溶解膜蛋白和受体。它有助于打破蛋白质-蛋白质相互作用。它是天然存在的胆汁盐的衍生物。[1]其胶束分子量较小(6,150)、临界胶束浓度很高(6-10 mM),因此可通过透析从样品中去除。

应用

CHAPS的用途:
  • 用于细胞膜透化[2]
  • 作为裂解缓冲液中的组分,用于肝组织和脂肪组织均质化[3][4]
  • 作为酶表征变性缓冲液的组分[5]
  • 作为2D电泳中2D-样品缓冲液的组分[6]
  • 用于等电聚焦中的蛋白溶解[7]

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Acute Tox. 4 Oral

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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其他客户在看

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Ciechomska, et al.
Autophagy, 3(6), 586-590 (2007)
Effect of copper nanoparticles exposure in the physiology of the common carp (Cyprinus carpio): Biochemical, histological and proteomic approaches.
Gupta Y, et al.
Aquaculture and Fisheries, 1, 15-23 (2016)
Investigation of protein-tyrosine phosphatases by in-gel assays.
Markova B, et al.
Methods, 35(1), 22-27 (2005)
Qingchuan Zhao et al.
Cancer immunology research, 8(4), 544-555 (2020-02-13)
High-grade serous ovarian cancer (HGSC), the principal cause of death from gynecologic malignancies in the world, has not significantly benefited from advances in cancer immunotherapy. Although HGSC infiltration by lymphocytes correlates with superior survival, the nature of antigens that can

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. How do I store CHAPS, once it's dissolved in H2O?

    1 answer
    1. Solutions prepared at 100 mM in water are stable for at least 1 year when stored refrigerated. Note that a prepared solution is available. Please see the link below to review:
      https://www.sigmaaldrich.com/product/sigma/19899

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