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C3646

Sigma-Aldrich

壳聚糖

from shrimp shells, ≥75% (deacetylated)

别名:

聚（D-氨基葡萄糖）, 脱乙酰几丁质

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25 G
$107.00
10 G
$112.00
100 G
$418.00
500 G
$1,130.00

$107.00

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选择尺寸

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25 G
$107.00
10 G
$112.00
100 G
$418.00
500 G
$1,130.00

About This Item

CAS号:
9012-76-4
MDL號碼:
MFCD00161512
分類程式碼代碼:
12352201
NACRES:
NA.25

$107.00

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生物源

shrimp shells

品質等級

200

化驗

≥75% (deacetylated)

形狀

powder or flakes

顏色

white to beige

mp

102.5  °C ((216.5 °F ))

溶解度

acetic acid: water: 10 mg/mL, slightly hazy to hazy (with extensive sonication)
H2O: insoluble
organic solvents: insoluble

體積密度

0.15‑0.3 g/cm3

儲存溫度

room temp

SMILES 字串

N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4N)O)O[C@@H]5O[C@@H]([C@H]([C@@H]([C@H]5N)O)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6N)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7N)O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8N)O)O[C@@H]9O[C@@H]([C@H](

InChI

1S/C56H103N9O39/c1-87-56(86)65-28-38(84)46(19(10-74)96-55(28)104-45-18(9-73)95-49(27(64)37(45)83)97-39-12(3-67)88-47(85)20(57)31(39)77)103-54-26(63)36(82)44(17(8-72)94-54)102-53-25(62)35(81)43(16(7-71)93-53)101-52-24(61)34(80)42(15(6-70)92-52)100-51-23(60)33(79)41(14(5-69)91-51)99-50-22(59)32(78)40(13(4-68)90-50)98-48-21(58)30(76)29(75)11(2-66)89-48/h11-55,66-85H,2-10,57-64H2,1H3,(H,65,86)/t11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48+,49+,50+,51+,52+,53+,54+,55+/m1/s1

InChI 密鑰

FLASNYPZGWUPSU-SICDJOISSA-N

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相关类别

應用

与多价阴离子形成凝胶。 产生透明溶液，干燥后形成坚固、透明的薄膜。
虾壳衍生的壳聚糖、脱乙酰几丁质（聚β-1,4-D-葡糖胺）可用作生物相容、抗菌和环境友好的聚电解质生物材料，其具有多种应用，包括用于水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。它可以通过衍生化以进一步扩展其用途。[1][2]

特點和優勢

生物相容、抗菌和环保的聚电解质，其具有多种应用，包括水处理、色谱法、化妆品添加剂、抗微生物活性的纺织品处理、纺织品的新型纤维、照相纸、可生物降解的薄膜、生物医学装置、以及用于药物递送中控制释放的微胶囊植入物。

品質

可能含有杂质。

準備報告

通过从虾（Pandalus borealis）壳中获得的几丁质，经过碱性脱乙酰化制备得到。在工业上，甲壳素是通过压碎虾壳，然后用酸将固体进行洗涤以除去无机和蛋白类物质而进行制造的。再通过强碱（如氢氧化钠）的处理，将纯化的几丁质脱乙酰化成壳聚糖。所得的壳聚糖可以通过在酸中溶解，然后中和和沉淀来进一步纯化。

分析報告

乙酰化程度可以通过与染料结合[3] 或滴定的方法[4]来确定。

其他說明

为了全面了解我们针对客户研究提供的各种多糖产品，建议您访问我们的碳水化合物分类页面。

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

nwg

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000336069
0000334001
0000334000
0000333999
0000323335

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Sirong Tan et al.
Journal of agricultural and food chemistry, 62(8), 1866-1874 (2014-02-01)
Chitosan (CTS) and capsaicin (CAP) are two kinds of effective ingredients for antiobesity, which are extracted from crab shells and Capsicum annuum. However, the strong taste of CAP makes it difficult to consume, and the antiobesity ability of CTS is
Frederik T Larsen et al.
Vaccines, 8(2) (2020-05-21)
Infectious bronchitis virus (IBV) is a highly contagious avian coronavirus. IBV causes substantial worldwide economic losses in the poultry industry. Vaccination with live-attenuated viral vaccines, therefore, are of critical importance. Live-attenuated viral vaccines, however, exhibit the potential for reversion to
Wen-Chu Hsiao et al.
Journal of the Formosan Medical Association = Taiwan yi zhi, 118(1 Pt 1), 152-161 (2018-03-04)
Cell behaviors in three-dimensional spheroids are known to be different from those in monolayer cultures; however, very few studies have compared the characteristics of cell spheroids formed through different biomaterial-induced processes. This study investigated the mechanism of melanocyte spheroid formation
Determination of the degree of acetylation of chitin and chitosan.
Davies, D. H., and Hayes, E. R.
Methods in Enzymology, 161-pt. B, 442-446 (1988)
Koen van der Maaden et al.
Langmuir : the ACS journal of surfaces and colloids, 30(7), 1812-1819 (2014-01-30)
The aim of this work was to generate a tunable surface isoelectric point (sIEP), where the surface is modified with two molecules: a weak base (pyridine), carrying a pH dependent positive charge, and a derivative of a strong acid (sulfate)
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Questions

1–7 of 7 Questions  

  1. C3646 chitosan is lower molecular weight? What is the molecular weight range?

    1 answer

    1. This product is not considered a low molecular weight option. The material is a fairly crude, practical grade. Historical data indicates an estimated molecular weight range of 190 - 375 kDa.

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  5. What is the molecular weight of Product C3646, Chitosan from shrimp shells?

    1 answer

    1. Sigma-Aldrich has not determined an average molecular weight or a molecular weight range for this product.

      Helpful?

  6. Is Product C3646, Chitosan from shrimp shells, USP grade?

    1 answer

    1. No, this product is not considered USP grade.

      Helpful?

  7. What is the pKa of Product C3646, Chitosan from shrimp shells?

    1 answer

    1. The amino group in chitosan has a pKa value of ~6.5.

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