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Merck

A7661

Sigma-Aldrich

N-Acetyl-D-glucosamin-6-sulfat 钠盐

≥97% (HPAE)

别名:

GlcNAc-6S

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About This Item

线性分子式:
C8H14NO9SNa
分子量:
323.25
MDL號碼:
分類程式碼代碼:
12352201
PubChem物質ID:

描述

Mixed anomers

化驗

≥97% (HPAE)

形狀

powder

儲存溫度

2-8°C

SMILES 字串

[Na+].CC(=O)N[C@H]1C(O)O[C@H](COS([O-])(=O)=O)[C@@H](O)[C@@H]1O

InChI

1S/C8H15NO9S.Na/c1-3(10)9-5-7(12)6(11)4(18-8(5)13)2-17-19(14,15)16;/h4-8,11-13H,2H2,1H3,(H,9,10)(H,14,15,16);/q;+1/p-1/t4-,5-,6-,7-,8?;/m1./s1

InChI 密鑰

CBUJZKTVEFVBBG-FROKLYQUSA-M

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應用

N-Acetyl-D-glucosamine 6-sulfate (GlcNAc-6S) is used as a substrate and inhibitor to identify, differentiate and characterize various sulfatase(s), especially N-acetylglucosamine-6-sulphatase(s).

儲存類別代碼

13 - Non Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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Andrew J Nok et al.
Journal of biochemical and molecular toxicology, 17(1), 59-66 (2003-03-05)
The venom of Naja nigricolis was found to contain a high level of the enzyme aryl sulfatase. The enzyme was isolated from the venom of N. nigriclois and purified to electrophoretic homogeneity by gel chromatography on Sephadex G-100, DEAE-cellulose, and
Andrea Mok et al.
Genomics, 81(1), 1-5 (2003-02-08)
Mucopolysaccharidosis type IIID (MPS IIID; Sanfilippo syndrome type D; MIM 252940) is caused by deficiency of the activity of N-acetylglucosamine-6-sulfatase (GNS), which is normally required for degradation of heparan sulfate. The clinical features of MPS IIID include progressive neurodegeneration, with
Shengyuan Xu et al.
The Biochemical journal, 387(Pt 3), 841-847 (2004-12-15)
A 75 kDa protein was purified to homogeneity from granule extracts of normal human granulocytes using Sephadex G-75 chromatography, Mono-S cation exchange chromatography and chromatofocusing. The protein consisted of one chain with a molecular mass of 75 kDa, as determined

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