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Merck

95904

Sigma-Aldrich

聚(乙二醇)

BioUltra, 4,000

别名:

PEG

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250 G
$120.00
1 KG
$247.00

$120.00


国内现货,预计发货时间2025年4月07日详情


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250 G
$120.00
1 KG
$247.00

About This Item

线性分子式:
H(OCH2CH2)nOH
CAS号:
MDL编号:
UNSPSC代码:
12352104
PubChem化学物质编号:
NACRES:
NA.26

$120.00


国内现货,预计发货时间2025年4月07日详情


获取大包装报价

产品线

BioUltra

表单

powder

分子量

Mr 3500-4500

杂质

insoluble matter:, passes filter test
≤0.001% peroxides (as H2O2):

pH值(酸碱度)

5.5-7.0 (25 °C, 50 mg/mL in H2O)

mp

58-61 °C

溶解性

H2O: 50 mg/mL at 25 °C, clear, colorless

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

痕量阳离子

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤10 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤200 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤200 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

λ

50 mg/mL in H2O

紫外吸收

λ: 260 nm Amax: ≤0.10
λ: 280 nm Amax: ≤0.04

SMILES字符串

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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一般描述

聚乙二醇(PEG)是乙二醇聚合物,具有亲水性。PEG结构灵活并且具有高水合能力。由于PEG具有生物相容性并且结构中不存在空间位阻。[1]美国食品和药品监督管理局(FDA)批准PEG用作药物结合物。它是非免疫原性且安全的。[2]PEG结合改善了糖尿病药物格列齐特的溶解度和溶出度。[3]PEG被广泛用作生物化学和分子生物学实验的试剂。[4]它被用于碳纳米管官能化。[5]

应用

聚乙二醇已被用作:
  • 小麦原生质体分离和转化缓冲液的组分[6]
  • 悬浮细胞培养物的添加剂[7]
  • 酵母转化缓冲液的组分[8]
  • 半胱氨酸蛋白酶ATG4B结晶化缓冲液的组分[9]

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

281.5 °F - closed cup

闪点(°C)

138.6 °C - closed cup

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Immunogenicity of polyethylene glycol (PEG)
Garay RP and Labaune JP
The open conference proceedings journal, 2(1), 1257-1275 (2011)
ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8
Rasmussen MS, et al.
Autophagy, 13(5), 834-834 (2017)
Characterisation of gliclazide-PEG 8000 solid dispersions
Biswal S, et al.
Tropical Journal of Pharmaceutical Research, 8(5), 260-260 (2009)
Genome editing of bread wheat using biolistic delivery of CRISPR/Cas9 in vitro transcripts or ribonucleoproteins
Liang Z, et al.
Nature Protocols, 13(3), 413-413 (2018)
Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs
Dong S, et al.
Nature Protocols, 5(3), 561-561 (2010)

相关内容

Polyethylene glycol (PEG), also sometimes referred to as polyethylene oxide (PEO), is a condensation polymer of ethylene oxide and water that has several chemical properties that make it useful for biological, chemical and pharmaceutical applications.

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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