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Merck

95144

Sigma-Aldrich

视黄醇

BioXtra, ≥97.5% (HPLC), ~3100 U/mg

别名:

全反式-3,7-二甲基-9-(2,6,6-三甲基-1-环己烯-1-基)-2,4,6,8-壬四烯-1-醇, 抗干眼醇, 维生素 A, 维生素 A 醇, 维生素 A1

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250 MG
$373.00
1 G
$1,060.00

$373.00


国内现货,预计发货时间2025年4月07日详情


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250 MG
$373.00
1 G
$1,060.00

About This Item

经验公式(希尔记法):
C20H30O
CAS号:
分子量:
286.45
Beilstein:
403040
EC 号:
MDL编号:
UNSPSC代码:
12352205
eCl@ss:
34058018
PubChem化学物质编号:
NACRES:
NA.28

$373.00


国内现货,预计发货时间2025年4月07日详情


获取大包装报价

生物来源

synthetic

产品线

BioXtra

方案

≥97.5% (HPLC)

表单

(Powder or Powder with Lumps)

比活

~3100 U/mg

保质期

limited shelf life

颜色

faint yellow to very dark yellow

mp

56-61 °C
61-63 °C (lit.)

运输

dry ice

储存温度

−20°C

SMILES字符串

CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/CO)=C(C)CCC1

InChI

1S/C20H30O/c1-16(8-6-9-17(2)13-15-21)11-12-19-18(3)10-7-14-20(19,4)5/h6,8-9,11-13,21H,7,10,14-15H2,1-5H3/b9-6+,12-11+,16-8+,17-13+

InChI key

FPIPGXGPPPQFEQ-OVSJKPMPSA-N

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一般描述

视黄醇或维生素A醇是维生素A的主要循环形式。[1]

应用

视黄醇已用于:
  • 用作反相HPLC中的峰鉴定和定量标准品[2]
  • 用作预估维生素A浓度的标准品[3]
  • 研究视黄醇对鼠RAW 264.7细胞中鼠诺如病毒(MNV)复制的抑制作用[4]
  • 用作卵磷脂:视黄醇酰基转移酶(LRAT)测定反应混合物组分[5]

生化/生理作用

它没有生物活性,并且是活性类视黄醇的前体。视黄醇可转化为视黄醛,然后再转化为视黄酸。[1]
视网膜的视黄醇和视黄酸是一种醛,是维生素A的醇和酸形式。类视黄醇存在许多空间异构体,因为它的脂肪链有不饱和键。
视黄醇在多种过程中有生物活性。

包装

无底玻璃瓶。内容物在插入式融锥内。

单位定义

1U相当于对Ph Eur II, 217 1国际U(1983)

象形图

Health hazardExclamation mark

警示用语:

Danger

危险分类

Aquatic Chronic 4 - Eye Irrit. 2 - Repr. 1B - Skin Sens. 1

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Understanding the physiological role of retinol-binding protein in vitamin A metabolism using transgenic and knockout mouse models
Quadro L, et al.
Molecular Aspects of Medicine, 24(6), 421-430 (2003)
Antiviral effect of vitamin A on norovirus infection via modulation of the gut microbiome
Lee H and Ko G
Scientific reports, 25835-25835 (2016)
Retinyl palmitate does not have an adjuvant effect on the antibody response of chicks to keyhole limpet hemocyanin regardless of vitamin A status
Livingston KA and Klasing KC
Poultry Science, 90(5), 965-970 (2011)
Heetae Lee et al.
Scientific reports, 6, 25835-25835 (2016-05-18)
The effect and underlying mechanism of vitamin A on norovirus infection are largely unknown. This study aimed to investigate how vitamin A administration affects the gut microbiome after norovirus infection. Here, we demonstrate that treatment with either retinol or retinoic
Responses of blood metabolites and proteins to different vitamin A levels in Korean native steers.
Wang T, et al.
Pakistan journal of botany, 34(4) (2014)

实验方案

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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