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Merck
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文件

85865

Sigma-Aldrich

Stigmatellin

≥95.0% (HPLC)

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About This Item

经验公式（希尔记法）:
C30H42O7
CAS号:
91682-96-1
分子量:
514.65
Beilstein:
5319239
MDL號碼:
MFCD00077874
分類程式碼代碼:
51101500
PubChem物質ID:
24888469

化驗

≥95.0% (HPLC)

抗生素活性譜

fungi

作用方式

enzyme | inhibits

運輸包裝

wet ice

儲存溫度

−20°C

SMILES 字串

COC(\C=C\C=C\C(C)=C\C)C(C)C(OC)C(C)CCC1=C(C)C(=O)c2c(OC)cc(OC)c(O)c2O1

生化／生理作用

Antibiotic and antifungal from Stigmatella aurantiaca. Inhibits electron transport. Acts at the Qo center of the bc1 complex, binds to the heme b1 domain of cytochrome b as well as to the iron-sulfur protein. Used in studies on hydroubiquinone-cytochrome c2 oxidoreductase.

包裝

Bottomless glass bottle. Contents are inside inserted fused cone.

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Use of specific inhibitors on the mitochondrial bc1 complex.
G von Jagow et al.
Methods in enzymology, 126, 253-271 (1986-01-01)
D E Robertson et al.
Biochemistry, 32(5), 1310-1317 (1993-02-09)
The hydroubiquinone-cytochrome c2 oxidoreductase (cyt bc1) from Rhodobacter capsulatus has been solubilized according to the dodecyl maltoside method and isolated, and its minimal functional composition has been characterized. We find the complex to be composed of three protein subunits corresponding
B Kunze et al.
The Journal of antibiotics, 37(5), 454-461 (1984-05-01)
An antibiotic activity was extracted from the cell mass of the myxobacterium, Stigmatella aurantiaca strain Sg a15. The antibiotic was toxic for yeasts and filamentous fungi, but not for most bacteria. The compound had the molecular formula C30H42O7, appears to

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