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Merck

58756

Sigma-Aldrich

1-(5-Isoquinolinesulfonyl)-3-methylpiperazine

≥98.0% (HPLC)

别名:

1-(5-硫代异喹啉)-3-甲基哌嗪, Iso-H-7

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About This Item

经验公式(希尔记法):
C14H17N3O2S
CAS号:
分子量:
291.37
Beilstein:
5445506
MDL號碼:
分類程式碼代碼:
12352202
PubChem物質ID:
NACRES:
NA.77

化驗

≥98.0% (HPLC)

形狀

powder

儲存溫度

2-8°C

SMILES 字串

CC1CN(CCN1)S(=O)(=O)c2cccc3cnccc23

InChI

1S/C14H17N3O2S/c1-11-10-17(8-7-16-11)20(18,19)14-4-2-3-12-9-15-6-5-13(12)14/h2-6,9,11,16H,7-8,10H2,1H3

InChI 密鑰

QGSCXAWTTISKLF-UHFFFAOYSA-N

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生化/生理作用

Less potent inhibitor of protein kinaseC than H-7

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


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J Duraj et al.
Neoplasma, 44(4), 205-211 (1997-01-01)
The human pre-B acute lymphoblastic leukemia cell line REH6 was utilized for characterization of CD45 glycoprotein by monoclonal antibodies (mAb) recognizing four distinct CD45 antigen specificities, i.e. nonrestricted CD45, restricted CD45RA, CD45RB and CD45R0. Immunoprecipitation revealed two antigen specificities on
C D Balaban et al.
Brain research, 845(1), 97-101 (1999-10-26)
This study tests the hypothesis that activation of protein kinase C (PKC) is a critical step for early recovery from spontaneous nystagmus after unilateral ablation of the vestibular periphery. Halothane-NO(2)-O(2)-anesthetized Long-Evans rats received a 5-microl intracerebroventricular bolus of vehicle (distilled
H Takahashi et al.
Biological & pharmaceutical bulletin, 20(4), 446-448 (1997-04-01)
Capric acid (C10) enhanced the absorption of cefoxitin sodium in a concentration-dependent manner following the rectal administration as a suppository in rats. The optimal concentration of C10 was 13%. C10 administered as a suppository also reduced rectal membrane resistance (Rm)
L B Quesnel et al.
The Journal of antimicrobial chemotherapy, 41(2), 215-221 (1998-04-09)
Cystic fibrosis (CF) results from mutations in the gene encoding the CF transmembrane conductance regulator (CFTR) which is a regulated chloride channel. The deltaF508 mutation prevents the post-translational glycosylation and membrane insertion of the protein. Severe disease follows, with the
B L Sailer et al.
Cytometry, 31(3), 208-216 (1998-03-27)
Fluorescence lifetime analysis was used in combination with conventional flow cytometric analysis to monitor changes in residual chromatin in apoptotic HL-60 cell populations following treatment with camptothecin, cycloheximide, genistein, H7, and gamma radiation. Data presented show that all of these

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