40674

松脂醇

≥95.0% (HPLC)

• 别名: (+)-松脂醇, 4,4′-((1S,3aR,4S,6aR)-六氢呋喃[3,4-c]呋喃-1,4-二基)双(2-甲氧基苯酚), 4,4′-[(1S,3aR,4S,6aR)-四氢-1H,3H-呋喃[3,4-c]呋喃-1,4-二基]双(2-甲氧基苯酚) )
• 经验公式（希尔记法）: C₂₀H₂₂O₆
• CAS号: 487-36-5
• 分子量: 358.39
• MDL编号: MFCD07784516
• UNSPSC代码: 12352205
• PubChem化学物质编号: 329756010
• NACRES: NA.25

属性

• 方案: ≥95.0% (HPLC)
• 表单: powder or crystals
• 应用: metabolomics; vitamins, nutraceuticals, and natural products
• SMILES字符串: COc1cc(ccc1O)[C@H]2OC[C@H]3[C@@H]2CO[C@@H]3c4ccc(O)c(OC)c4
• InChI: 1S/C20H22O6/c1-23-17-7-11(3-5-15(17)21)19-13-9-26-20(14(13)10-25-19)12-4-6-16(22)18(8-12)24-2/h3-8,13-14,19-22H,9-10H2,1-2H3/t13-,14-,19+,20+/m0/s1
• InChI key: HGXBRUKMWQGOIE-AFHBHXEDSA-N

说明

一般描述

Pinoresinol is a secondary metabolite, a lignan found in wide varieties of plants.[1] Structurally, it is one of the simple lignans, with a dimer of coniferyl alcohol, which forms the bicyclic ring core.[1]

应用

Pinoresinol has been used:

• as a reference standard for qualitative and quantitative analysis of lignans from Triticale (X Triticosecale Wittmack) grains using ultra-performance liquid chromatography (UPLC) with photodiode and mass TQD detectors[2]
• as an enterolignan precursor to study its estrogenic activity on the proliferation of human breast cancer MCF-7 cells[3]
• as a reference standard for lignan analysis of Sesamum indicum L. seeds[4]

生化/生理作用

松脂素存在于包括药用植物在内的多种植物中，如水生接骨木、杜仲、安息香属、连翘以及特级初榨橄榄油中。其中的接骨木属广泛分布于欧洲、亚洲和北非，并已在传统医学中作为止痛药、抗病毒药、抗炎药、止血药和利尿药用于瘀伤、骨折和水肿。松脂素可通过引起真菌质膜的损伤而显示出有效的抗真菌特性。它通过抑制TNF-α的产生（很可能是通过抑制NF- κB和AP-1）而发挥出抗氧化和抗炎的作用。

通过抑制TNF-α的产生而发挥出抗氧化和抗炎的作用。

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable