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Merck

M79603

Sigma-Aldrich

NMP

ReagentPlus®, 99%

别名:

N-甲基-2-吡咯烷酮, N-甲基吡咯烷酮, NMP

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About This Item

经验公式(希尔记法):
C5H9NO
CAS号:
分子量:
99.13
Beilstein:
106420
EC號碼:
MDL號碼:
分類程式碼代碼:
12352005
PubChem物質ID:
NACRES:
NA.21

product name

1-甲基-2-吡咯烷酮, ReagentPlus®, 99%

蒸汽密度

3.4 (vs air)

品質等級

蒸汽壓力

0.29 mmHg ( 20 °C)
0.99 mmHg ( 40 °C)

產品線

ReagentPlus®

化驗

99%

形狀

liquid

自燃溫度

518 °F

expl. lim.

9.5 %

雜質

≤0.1% water (Karl Fischer)

顏色

APHA: ≤50

折射率

n20/D 1.47 (lit.)

pH值

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.)
81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

密度

1.028 g/mL at 25 °C (lit.)

SMILES 字串

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI 密鑰

SECXISVLQFMRJM-UHFFFAOYSA-N

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應用

与芳基硫代乙酰胺 和水杨酸甲酯发生缩合反应。多用途溶剂,用于水混溶性应用。

其他說明

Cyrene(807796)可用于许多NMP应用,是一种更环保的替代品。

法律資訊

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Health hazardExclamation mark

訊號詞

Danger

危險分類

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 1

閃點(°F)

195.8 °F - Pensky-Martens closed cup

閃點(°C)

91 °C - Pensky-Martens closed cup


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U Isele et al.
Journal of pharmaceutical sciences, 83(11), 1608-1616 (1994-11-01)
This work describes the development of an organic solvent dilution method suitable for the large scale manufacturing of small unilamellar liposomes containing the water-insoluble photosensitizer zinc phthalocyanine in the monomeric state. N-Methyl pyrrolidone (NMP)/tert-butyl alcohol was selected as water miscible
The Journal of Organic Chemistry, 58, 7277-7277 (1993)
Journal of the Chemical Society. Chemical Communications, 1437-1437 (1994)
J. Mol. Catal., 85, L109-L109 (1993)
David S Hewings et al.
Journal of medicinal chemistry, 54(19), 6761-6770 (2011-08-20)
Histone-lysine acetylation is a vital chromatin post-translational modification involved in the epigenetic regulation of gene transcription. Bromodomains bind acetylated lysines, acting as readers of the histone-acetylation code. Competitive inhibitors of this interaction have antiproliferative and anti-inflammatory properties. With 57 distinct

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