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化驗
≥98% (HPLC)
品質等級
形狀
solid
溶解度
water: soluble
儲存溫度
2-8°C
InChI
1S/C6H6O4S.K/c7-11(8,9)10-6-4-2-1-3-5-6;/h1-5H,(H,7,8,9);/q;+1/p-1
InChI 密鑰
NOUFXYHWAWIDNT-UHFFFAOYSA-M
一般說明
Potassium phenyl sulfate is the salt of gut metabolite phenol sulfate.It is biosynthesized from phenol and phosphoadenosine phosphosulfate through the action of the enzyme sulfotransferase 1A1 in the liver. Also, it induces reactive oxygen species (ROS) production and decreases glutathione levels, rendering cells vulnerable to oxidative stress.
應用
Metabolomics research
Microbiome research
Microbiome research
其他說明
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儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
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分析证书(COA)
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PloS one, 13(2), e0193342-e0193342 (2018-02-24)
In chronic kidney disease patients, oxidative stress is generally associated with disease progression and pathogenesis of its comorbidities. Phenyl sulfate is a protein-bound uremic solute, which accumulates in chronic kidney disease patients, but little is known about its nature. Although
Nature communications, 10(1), 1835-1835 (2019-04-25)
Diabetic kidney disease is a major cause of renal failure that urgently necessitates a breakthrough in disease management. Here we show using untargeted metabolomics that levels of phenyl sulfate, a gut microbiota-derived metabolite, increase with the progression of diabetes in
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