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Merck

SMB00914

Sigma-Aldrich

Isovanillic Acid 3-Sulfate Disodium Salt

≥96% (HPLC)

别名:

Isovanillic acid 3-sulfate disodium salt

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About This Item

经验公式(希尔记法):
C8H6Na2O7S
CAS号:
分子量:
292.17
分類程式碼代碼:
12352205
NACRES:
NA.25

化驗

≥96% (HPLC)

形狀

powder

顏色

, White to off-white

溶解度

water: 40 mg/mL

儲存溫度

2-8°C

SMILES 字串

COC(C=C1)=C(OS(=O)(O[Na])=O)C=C1C(O[Na])=O

一般說明

Isovanillic acid 3-O-sulfate (IVAS) is a gut microbial phenolic metabolite primarily derived from consumed cyanidin 3-O-glucoside, a major compound in berry fruits. IVAS is the most effective among the gut microbial phenolic metabolites tested to enhance glucose uptake & metabolism in human skeletal muscle myoblast LHCN-M2. IIVAS is shown to increase glucose transport via GLUT4- and PI3K-dependent mechanisms. IVAS also upregulates GLUT1, GLUT4, PI3K p85a protein level, and Akt phosphorylation, establishing a novel link between gut microbiota, host diet and skeletal muscle energy source utilization.Also another study shows that IVAS restores glycosaminoglycans (GAGs) level and reduce inflammatory markers in diabetic human aortic endothelial cells (HAECs).

其他說明

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儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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