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Merck

PHR1738

Supelco

布比卡因相关化合物A

Pharmaceutical Secondary Standard; Certified Reference Material

别名:

6-(butylamino)-N-(2,6-dimethylphenyl)hexanamide (Bupivacaine Related Compound A) (Bupivacaine Impurity E)

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About This Item

分類程式碼代碼:
41116107
NACRES:
NA.24

等級

certified reference material
pharmaceutical secondary standard

品質等級

agency

traceable to Ph. Eur. Y0000089
traceable to USP 1078518

API 家族

bupivacaine

CofA

current certificate can be downloaded

包裝

pkg of 40 mg

應用

pharmaceutical (small molecule)

格式

neat

儲存溫度

2-8°C

一般說明

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Bupivacaine and its derivatives are a category of compounds that are used as local anesthetics. Its applications consist of infiltration, nerve block, epidural, and intrathecal anesthesia.

應用

Bupivacaine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析報告

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他說明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

腳註

To see an example of a Certificate of Analysis for this material enter LRAA7909 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

象形圖

Skull and crossbones

訊號詞

Danger

危險聲明

危險分類

Acute Tox. 3 Oral - Aquatic Chronic 4

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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分析证书(COA)

Lot/Batch Number

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Protein synthesis in bupivacaine (Marcaine)-treated, regenerating skeletal muscle
Jones GH
Muscle and Nerve, 5(4), 281-290 (1982)
Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system
Wang D, et al.
The Spine Journal : Official Journal of the North American Spine Society, 11(2), 139-146 (2011)
Determination of tramadol, metamizole, ropivacaine, and bupivacaine in analgesic mixture samples by HPLC with DAD detection
Salmeron-Garcia A, et al.
Journal of Chromatographic Science, 47(3), 231237-231237 (2009)
Quantitative mass spectrometric analysis of ropivacaine and bupivacaine in authentic, pharmaceutical and spiked human plasma without chromatographic separation
Salama NN and Wang S
Analytical Chemistry Insights, 4(3), ACI-S2564 (2009)

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