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Merck

C9481

Sigma-Aldrich

羧甲纤维素 钠

Carboxymethylcellulose sodium

meets USP testing specifications, Medium viscosity

别名:

羧甲基纤维素 钠盐, 羧甲基纤维素钠

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500 G
$301.00
1 KG
$353.00

$301.00


国内现货,预计发货时间2025年4月07日详情


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500 G
$301.00
1 KG
$353.00

About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352201
NACRES:
NA.21

$301.00


国内现货,预计发货时间2025年4月07日详情


获取大包装报价

Agency

USP/NF
meets USP testing specifications

质量水平

方案

6.5-9.5% anhydrous basis (Sodium)

表单

powder

颜色

light yellow

pH值(酸碱度)

(10 g/L68 °F neutral)

粘度

400-800 cP, 2 % in H2O(25 °C)(lit.)

mp

> 300.05  °C ((> 572.09 °F ))

溶解性

water: soluble

SMILES字符串

[Na].OC(C(O)C(O)C=O)C(O)CO.OC(=O)C

InChI

1S/C6H12O6.C2H4O2.Na/c7-1-3(9)5(11)6(12)4(10)2-8;1-2(3)4;/h1,3-6,8-12H,2H2;1H3,(H,3,4);

InChI key

DPXJVFZANSGRMM-UHFFFAOYSA-N

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一般描述

羧甲基纤维素钠是一种粘性多糖,属于高分子量类别。具有黏附性,可在眼科手术中使用。羧甲基纤维素钠促进角膜伤口上皮细胞的重新上皮化。[1]对于研究贴壁细胞和三维组织培养模型非常有用。[2]

应用

对于研究贴壁细胞和三维组织培养模型非常有用。
羧甲基纤维素钠作为载体,用于枸橼酸他莫昔芬、[3] 索拉非尼、[4] 和沃利替尼。[5]也作为无血清培养基(SFM)的成分,用于悬浮人脐静脉内皮细胞。[6]

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Carboxymethylcellulose binds to human corneal epithelial cells and is a modulator of corneal epithelial wound healing
Garrett Q, et al.
Investigative Ophthalmology & Visual Science, 48(4), 1559-1567 (2007)
Anti-estrogen resistance in human breast tumors is driven by JAG1-NOTCH4-dependent cancer stem cell activity
Simoes BM, et al.
Testing, 12(12), 1968-1977 (2015)
Vascular CXCR4 expression promotes vessel sprouting and sensitivity to sorafenib treatment in hepatocellular carcinoma
Xu J, et al.
Clinical Cancer Research, 23(15), 4482-4492 (2017)
The MET inhibitor AZD6094 (Savolitinib, HMPL-504) induces regression in papillary renal cell carcinoma patient-derived xenograft models
Schuller AG, et al.
Clinical Cancer Research, 21(12), 2811-2819 (2015)
Recent advances in modified cellulose for tissue culture applications
Courtenay J, et al.
Molecules (Basel), 23(3), 654-654 (2018)

Questions

1–5 of 5 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. I need this product information about Molecular weight. 분자량 범위 정보 필요

    1 answer
    1. The molecular weight of this product is 250 kDa.

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  4. What is the expiration/shelf life/retest date of this product? The Certificate of Analysis does not list any information about it for individual lots. Thank you!

    1 answer
    1. This product is not assigned an expiration date or recommended retest date. Products with no expiration date or recommended retest date should be routinely inspected by customers to ensure they perform as expected. These products are also subject to a one year warranty from the date of shipment. For more information you may access the "Product Dating Information" document under "ADDITIONAL USEFUL DOCUMENTS ABOUT OUR PRODUCTS" at the bottom of the Quality Services page with this link: https://www.sigmaaldrich.com/life-science/quality-and-regulatory-management/quality-services.

      Helpful?

  5. I have a question regarding the degree of substitution of product C9481. As you know, the degree of substitution of CMC is an important characteristic. Have a wonderful day.

    1 answer
    1. The degree of substitution of this item is 0.7 (approximately 7 carboxymethyl groups per 10 anhydroglucose units).

      Helpful?

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