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Merck
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91801

Supelco

洋蓟素

analytical standard

别名:

1,3-二咖啡酰奎宁酸, (1R,3R,4S,5R)-1,3-双[[3-(3,4-二羟基苯基)-1-氧代-2-丙烯-1-基]氧基]-4,5-二羟基环己烷甲酸, 1,5-DQA, 1,5-二咖啡酰奎宁酸, 洋蓟素

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About This Item

经验公式（希尔记法）:
C25H24O12
CAS号:
30964-13-7
分子量:
516.45
MDL编号:
MFCD11112054
UNSPSC代码:
85151701
PubChem化学物质编号:
329770082
NACRES:
NA.24

等级

analytical standard

质量水平

100

方案

≥98.0% (HPLC)

保质期

limited shelf life, expiry date on the label

技术

HPLC: suitable
gas chromatography (GC): suitable

杂质

≤10.0% water

应用

food and beverages

包装形式

neat

储存温度

2-8°C

SMILES字符串

O[C@@H]1C[C@](C[C@@H](OC(=O)\C=C\c2ccc(O)c(O)c2)[C@H]1O)(OC(=O)\C=C\c3ccc(O)c(O)c3)C(O)=O

InChI

1S/C25H24O12/c26-15-5-1-13(9-17(15)28)3-7-21(31)36-20-12-25(24(34)35,11-19(30)23(20)33)37-22(32)8-4-14-2-6-16(27)18(29)10-14/h1-10,19-20,23,26-30,33H,11-12H2,(H,34,35)/b7-3+,8-4+/t19-,20-,23+,25-/m1/s1

InChI key

YDDUMTOHNYZQPO-RVXRWRFUSA-N

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一般描述

洋蓟素是洋蓟植物的活性成分，具有利胆和降胆固醇活性。它还广泛用于草药方剂，用于治疗肝病中的特殊适应症。[1]

应用

有关合适仪器技术的更多信息，请参考产品′s分析证书。如需进一步支持，请联系技术服务。
洋蓟素可作为分析标准品，通过高效液相色谱技术对血浆样品中的分析物进行定量分析。[1]

生化/生理作用

在朝鲜蓟中发现的酚类化合物。抗氧化和利胆作用。潜在的免疫抑制剂。

包装

无底玻璃瓶。内容物在插入式融锥内。

其他说明

This compound is commonly found in plants of the genus: arnica echinacea

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCJ6840
BCCJ3110
BCCH2885
BCCH0749
BCCG5924

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Validated HPLC method for cynarin determination in biological samples
Alonso RM, et al.
Acta Acad. Med. Sin., 25(2), 267-267 (2006)
Esra Erikel et al.
Journal of ethnopharmacology, 237, 171-181 (2019-03-21)
Cynarin is an artichoke phytochemical that possesses a variety of pharmacological features including free-radical scavenging and antioxidant activity. The origin of artichoke species appears to be Mediterranean region. Two of these species, globe artichoke (Cynara cardunculus var. scolymus L.) and
Guo-Chung Dong et al.
Journal of medicinal chemistry, 49(6), 1845-1854 (2006-03-17)
AFTIR (after flowing through immobilized receptor) is a novel method for screening herbal extracts for pharmaceutical properties. Using AFTIR, we identified Cynarin in Echinacea purpurea by its selective binding to chip immobilized CD28, a receptor of T-cells, which is instrumental
Yi Wang et al.
Bioorganic & medicinal chemistry letters, 21(23), 7064-7067 (2011-10-22)
The complex and highly impermeable cell wall of Mycobacterium tuberculosis (Mtb) is largely responsible for the ability of the mycobacterium to resist the action of chemical therapeutics. An L-rhamnosyl residue, which occupies an important anchoring position in the Mtb cell
Bianca Sperl et al.
Bioorganic & medicinal chemistry letters, 19(12), 3305-3309 (2009-05-12)
In this Letter, we report the natural products salvianolic acid A, salvianolic acid B, and caftaric acid as inhibitors of the protein-protein interactions mediated by the SH2 domains of the Src-family kinases Src and Lck, two established disease targets. Moreover
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