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描述
for ion-selective electrodes
质量水平
产品线
Selectophore™
方案
≥99.0% (GC)
≥99.0%
表单
liquid
折射率
n20/D 1.490
密度
1.025 g/mL at 20 °C (lit.)
SMILES字符串
CCCCCOC(=O)c1ccccc1C(=O)OCCCCC
InChI
1S/C18H26O4/c1-3-5-9-13-21-17(19)15-11-7-8-12-16(15)18(20)22-14-10-6-4-2/h7-8,11-12H,3-6,9-10,13-14H2,1-2H3
InChI key
IPKKHRVROFYTEK-UHFFFAOYSA-N
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一般描述
Dipentyl phthalate (DPeP) belongs to phthalate group, and is a dialkyl or aryl/alkyl diesters of phthalic acid.[1] It may be prepared from phthalic anhydride along with n-pentanol.[2]
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应用
- Biologically relevant reductions in fetal testosterone and Insl3 induced by in utero exposure to high levels of di-isononyl phthalate (DINP) in male rats: Dipentyl phthalate′s structural similarities to DINP underpin studies on phthalate exposure′s impacts on male reproductive health, providing insights into potential risks and mechanisms of toxicity in developmental stages (Earl Gray L Jr, 2023).
- Exposure to dipentyl phthalate in utero disrupts the adrenal cortex function of adult male rats by inhibiting SIRT1/PGC-1α and inducing AMPK phosphorylation: This study uses dipentyl phthalate to examine the adverse effects of phthalate exposure on adrenal gland function, contributing to a deeper understanding of metabolic disruptions (Chen et al., 2023).
- Determination of 15 phthalic acid esters based on GC-MS/MS coupled with modified QuEChERS in edible oils: This research demonstrates the utility of dipentyl phthalate in method development for detecting phthalates in food matrices, enhancing food safety assessments (Wang et al., 2022).
- Development of a putative adverse outcome pathway network for male rat reproductive tract abnormalities with specific considerations for the androgen sensitive window of development: Dipentyl phthalate is investigated for its role in developmental toxicity, aiding in the construction of models predicting reproductive health effects from chemical exposures (Palermo et al., 2021).
法律信息
Selectophore is a trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险声明
危险分类
Aquatic Acute 1 - Repr. 1B
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
244.4 °F - closed cup
闪点(°C)
118 °C - closed cup
个人防护装备
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
其他客户在看
M.M. Khalil
Analytical Letters, 26, 2071-2071 (1993)
Manori J Silva et al.
Chemosphere, 82(3), 431-436 (2010-10-19)
Di-n-pentyl phthalate (DPP) is used mainly as a plasticizer in nitrocellulose. At high doses, DPP acts as a potent testicular toxicant in rats. We administered a single oral dose of 500 mg kg(-1)bw of DPP to adult female Sprague-Dawley rats
T Granholm et al.
Journal of reproductive immunology, 21(1), 1-14 (1992-01-01)
Phthalate esters (PAE) are plasticizers in polyvinyl chloride plastics used, for example, in package material for medical solutions. PAE exposure is associated with testicular damage that primarily affects Sertoli cells, and is concomitant with leukocyte infiltration into the testicular interstitium.
S. Nomura
Analyst, 120, 503-503 (1995)
Xiaozhong Yu et al.
Toxicology and applied pharmacology, 239(3), 325-336 (2009-06-30)
Gonocytes exist in the neonatal testis and represent a transient population of male germ-line stem cells. It has been shown that stem cell self-renewal and progeny production is probably controlled by the neighboring differentiated cells and extracellular matrix (ECM) in
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