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About This Item
线性分子式:
HO2C(CH2)3CH(NH2)CO2H
CAS号:
分子量:
161.16
Beilstein:
1724348
MDL號碼:
分類程式碼代碼:
41116107
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等級
analytical standard
化驗
≥98% (TLC)
光學活性
[α]25/D 24±1°, c = 2 in 5 M HCl
儲存期限
limited shelf life, expiry date on the label
mp
203-205 °C (dec.) (lit.)
應用
clinical testing
格式
neat
SMILES 字串
N[C@@H](CCCC(O)=O)C(O)=O
InChI
1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
InChI 密鑰
OYIFNHCXNCRBQI-BYPYZUCNSA-N
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一般說明
L-2-Aminoadipic acid is the six-carbon homolog of glutamate and a metabolite of L-lysine.
應用
L-2-Aminoadipic acid may be used as an analytical standard in the following:
It may be used as an internal standard for the determination of free amino acids and ammonium ion contents in Crocus sativus L. from different geographical origins using high-performance liquid chromatography with diode array detection (HPLC-DAD).
- For the quantification of 2-aminoadipic acid in acid hydrolysates of processed skin samples using gas chromatography coupled to mass spectrometry (GC-MS).
- To investigate its effect on proteolysis and protein synthesis in C2C12 myotubes.
It may be used as an internal standard for the determination of free amino acids and ammonium ion contents in Crocus sativus L. from different geographical origins using high-performance liquid chromatography with diode array detection (HPLC-DAD).
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儲存類別代碼
13 - Non Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Determination of free amino acids and ammonium ion in saffron (Crocus sativus L.) from different geographical origins
Campo dPC, et al.
Food Chemistry, 114(4), 1542-1548 (2009)
Maho Shibata et al.
Investigative ophthalmology & visual science, 53(7), 3726-3732 (2012-05-17)
To investigate the involvement of glial cells in the autoregulation of optic nerve head (ONH) blood flow in response to elevated intraocular pressure (IOP). Rabbit eyes were treated with an intravitreal injection of l-2-aminoadipic acid (LAA), a gliotoxic compound. Twenty-four
David R Sell et al.
The Biochemical journal, 404(2), 269-277 (2007-02-23)
We hypothesized that the epsilon-amino group of lysine residues in longlived proteins oxidatively deaminates with age forming the carbonyl compound, allysine (alpha-aminoadipic acid-delta-semialdehyde), which can further oxidize into 2-aminoadipic acid. In the present study, we measured both products in insoluble
Regulatory effects of the L-lysine metabolites, L-2-aminoadipic acid and L-pipecolic acid, on protein turnover in C2C12 myotubes
Sato T, et al.
Bioscience, Biotechnology, and Biochemistry, 80(11), 2168-2175 (2016)
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