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等級
analytical standard
品質等級
化驗
≥99% (TLC)
技術
HPLC: suitable
gas chromatography (GC): suitable
mp
171-173 °C (lit.)
螢光
λex 360 nm; λem 450 nm (thiol adduct)
抗生素活性譜
mycobacteria
應用
forensics and toxicology
pharmaceutical (small molecule)
格式
neat
SMILES 字串
NNC(=O)c1ccncc1
InChI
1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
InChI 密鑰
QRXWMOHMRWLFEY-UHFFFAOYSA-N
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一般說明
化学结构式:吡啶
异烟肼是一类具有抗分枝杆菌活性的药物。用于结核病的治疗。
應用
参考产品的检验报告,了解更多关于合适仪器技术的信息。联系技术服务部寻求进一步支持。
生化/生理作用
针对结核菌的抗生素,抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和 细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性,在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。
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訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - Skin Irrit. 2
儲存類別代碼
11 - Combustible Solids
水污染物質分類(WGK)
WGK 3
個人防護裝備
dust mask type N95 (US), Eyeshields, Gloves
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