437573

N,N-二甲基甲酰胺

ACS reagent, ≥99.8%

• 别名: DMF, NSC 5356
• 线性分子式: HCON(CH₃)₂
• CAS号: 68-12-2
• 分子量: 73.09
• Beilstein: 605365
• EC 号: 200-679-5
• MDL编号: MFCD00003284
• UNSPSC代码: 12352111
• PubChem化学物质编号: 24867382
• 等级: ACS reagent
• 方案: ≥99.8%
• 技术: electrophoresis: suitable
• 沸点: 153 °C (lit.)
• 蒸汽压: 2.7 mmHg ( 20 °C)

属性

• 等级: ACS reagent
• 质量水平: 200
• 蒸汽密度: 2.5 (vs air)
• 蒸汽压: 2.7 mmHg ( 20 °C)
• 方案: ≥99.8%
• 表单: liquid
• 自燃温度: 833 °F
• expl. lim.: 15.2 %
• 技术: electrophoresis: suitable
• 杂质: ≤0.0005 meq/g Titr. acid; ≤0.003 meq/g Titr. base; ≤0.15% water
• 蒸发残留物: ≤0.005%
• 颜色: APHA: ≤15
• 折射率: n20/D 1.430 (lit.)
• pH值（酸碱度）: 6.7
• 沸点: 153 °C (lit.)
• mp: −61 °C (lit.)
• 溶解性: water: miscible
• 密度: 0.944 g/mL (lit.)
• SMILES字符串: [H]C(=O)N(C)C
• InChI: 1S/C3H7NO/c1-4(2)3-5/h3H,1-2H3
• InChI key: ZMXDDKWLCZADIW-UHFFFAOYSA-N

说明

一般描述

N,N-Dimethylformamide (DMF) is a polar organic solvent with a wide range of industrial applications.[1] It is a precursor for numerous reactions such as formylation, aminocarbonylation, amination, amidation and cyanation.[2] Along with phosphorus oxychloride, it forms Vilsmeier reagent used in the formylation of reactive aromatic and heteroaromatic substrates.[3] Dielectric relaxation experiments on DMF have been conducted between 238.15K and 338.15K.[4] The thermophysical properties of the molecular interactions between DMF and the ionic liquids, ammonium salts and imidazolium salts have been studied.[5] The characteristics of solute-solvent interactions between ammonium nitrate and DMF have been investigated.[6]

应用

多种疏水性有机化合物的溶剂。

N,N-Dimethylformamide (DMF) may be used in the following processes:

• As a solvent synthesis of gold nanoparticles.[7][8]
• As a solvent in capillary electrophoresis.[9]
• Regioselective synthesis of N,N-dimethylaminopyridzines by reacting with choropyridazines.[10]
• Synthesis of urea-N,N-dimethylformamide, a 3:1 solvate with urea.[11]

安全信息

• 象形图: GHS02,GHS08,GHS07
• 警示用语：: Danger
• 危险声明: H226,H312 + H332,H319,H360D
• 预防措施声明: P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313
• 危险分类: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - Repr. 1B
• 储存分类代码: 3 - Flammable liquids
• WGK: WGK 2
• 闪点(°F): 135.5 °F - closed cup
• 闪点(°C): 57.5 °C - closed cup
• 个人防护装备: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter