07858

(R)-3-氨基-1-叔丁氧羰基哌啶

≥98.0% (TLC)

• 别名: (R)-1-Boc-3-氨基哌啶, (R)-1-叔丁氧羰基-3-氨基哌啶
• 经验公式（希尔记法）: C₁₀H₂₀N₂O₂
• CAS号: 188111-79-7
• 分子量: 200.28
• MDL號碼: MFCD03094717
• 分類程式碼代碼: 12352005
• PubChem物質ID: 329748523
• NACRES: NA.22

属性

• 品質等級: 100
• 化驗: ≥98.0% (TLC)
• 光學活性: [α]/D -28.5±2°, c = 1 in DMF
• SMILES 字串: CC(C)(C)OC(=O)N1CCC[C@@H](N)C1
• InChI: 1S/C10H20N2O2/c1-10(2,3)14-9(13)12-6-4-5-8(11)7-12/h8H,4-7,11H2,1-3H3/t8-/m1/s1
• InChI 密鑰: AKQXKEBCONUWCL-MRVPVSSYSA-N

说明

一般說明

(R)-3-Amino-1-Boc-piperidine can be used as a precursor for the preparation of dipeptidyl peptidase IV inhibitors like linagliptin, alogliptin, and other antidiabetic agents.

應用

(R)-3-Amino-1-Boc-piperidine can be used to prepare a benzoxazepine derivative named (R)-7-(3,5-dimethoxyphenyl)-N-(piperidin-3-yl)-4-propionyl-2,3,4,5-tetrahydro-1,4-benzoxazepine-9-carboxamide, a potent CBP/P300 bromodomain inhibitor.

安全信息

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H302,H315,H319,H335
• 防範說明: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• 危險分類: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter