MABF155C

Anti-CD80 (mouse), APC, clone 16-10A1 Antibody

clone 16-10A1, from hamster(Armenian), Allophycocyanin conjugate

• 别名: T-lymphocyte activation antigen CD80, Activation B7-1 antigen (B7), CD80, CD80
• UNSPSC代码: 12352203
• eCl@ss: 32160702
• NACRES: NA.43

属性

• 生物来源: hamster (Armenian)
• 质量水平: 100
• 偶联物: Allophycocyanin conjugate
• 抗体形式: purified antibody
• 抗体产品类型: primary antibodies
• 克隆: 16-10A1, monoclonal
• 种属反应性: mouse
• 包装: antibody small pack of 25 μg
• 技术: flow cytometry: suitable
• 同位素/亚型: IgG
• UniProt登记号: Q00609
• 靶向翻译后修饰: unmodified
• 基因信息: mouse ... Cd80(12519)

说明

一般描述

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

应用

This Anti-CD80 (mouse), APC, clone 16-10A1 Antibody is validated for use in Flow Cytometry for the detection of CD80.

质量

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.06 μg from a representative lot detected CD80 in one million C57Bl/6 splenocytes.

其他说明

Concentration: Please refer to lot specific datasheet.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable