推荐产品
生物源
mouse
品質等級
抗體表格
ascites fluid
抗體產品種類
primary antibodies
無性繁殖
monoclonal
物種活性
human, mouse
製造商/商標名
Chemicon®
技術
ELISA: suitable
immunocytochemistry: suitable
western blot: suitable
同型
IgG2a
UniProt登錄號
運輸包裝
dry ice
目標翻譯後修改
unmodified
基因資訊
human ... PPARA(5465)
一般說明
过氧化物酶体增殖物激活受体(PPAR)是核激素受体,可以被多种化合物激活,包括原纤维、噻唑烷二酮、前列腺素和脂肪酸。已经描述了三种PPAR亚型,称为PPARα、PPARβ(也称为PPARδ)和PPARγ。PPAR通过与类固醇受体的类视黄醇X受体(RXR)家族成员形成异二聚体并与称为PPAR反应元件(PPRE)的特定DNA基序结合来促进转录。PPARα在原代肝细胞中含量很高,它调节参与脂肪酸代谢的蛋白质的表达。PPARβ是分布最广泛的亚型,通常以高水平表达。PPARγ主要存在于脂肪组织中,在调节脂肪细胞分化中起关键作用。
特異性
与过氧化物酶体增殖物激活受体α(PPARalpha)反应。与PPARbeta或PPARgamma无交叉反应。
免疫原
来自小鼠PPARalpha氨基酸18-34的合成肽。
應用
使用经ELISA、WB、ICC验证的抗PPAR α抗体(小鼠单克隆抗体)检测PPAR alpha,也称为过氧化物酶体增殖物激活受体α。
研究子类别
转录因子
转录因子
研究类别
表观遗传学&核功能
表观遗传学&核功能
蛋白质印迹:1:500-1:5000
免疫细胞化学:1:500-1:5000
ELISA:1:500-1:5,000
最佳工作稀释度必须由最终用户确定。
免疫细胞化学:1:500-1:5000
ELISA:1:500-1:5,000
最佳工作稀释度必须由最终用户确定。
外觀
腹水液。 液体。不含防腐剂。
儲存和穩定性
接收后,以未稀释的等分试样在-20°C下保存长达6个月。应避免反复冻/融循环。
分析報告
对照
3T3全细胞裂解物
3T3全细胞裂解物
法律資訊
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免責聲明
除非我们的目录或产品随附的其他公司文件中另有说明,否则我们的产品预期仅用于研究用途,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或对人类或动物的任何类型的消费或应用。
Not finding the right product?
Try our 产品选型工具.
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
閃點(°F)
Not applicable
閃點(°C)
Not applicable
Frontiers in nutrition, 8, 711398-711398 (2021-11-02)
Scope: Disruptions of circadian rhythm cause metabolic disorders and are closely related to dietary factors. In this study, we investigated the interplays between the dietary conjugated linoleic acid (CLA)-induced hepatic steatosis and the circadian clock regulation, in association with lipid
Nutrition & metabolism, 15, 86-86 (2018-12-18)
Non-alcoholic fatty liver disease (NAFLD) is a chronic and progressive liver disease with an increased risk of morbidity and mortality. However, so far no specific pharmacotherapy has been approved. Gynostemma pentaphylla (Thunb.) Makino (GP) is a traditional Chinese medicine that is
Scientific reports, 7(1), 174-174 (2017-03-12)
Diet plays a crucial role in shaping human health and disease. Diets promoting obesity and insulin resistance can lead to severe metabolic diseases, while calorie-restricted (CR) diets can improve health and extend lifespan. In this work, we fed mice either
Journal of cellular physiology, 236(6), 4387-4402 (2020-11-14)
Nonalcoholic-fatty-liver-disease (NAFLD) is the result of imbalances in hepatic lipid partitioning and is linked to dietary factors. We demonstrate that conjugated linoleic acid (CLA) when given to mice as a dietary supplement, induced an enlarged liver, hepatic steatosis, and increased
International journal of molecular sciences, 22(15) (2021-08-08)
Salivary gland cancers are rare but aggressive tumors that have poor prognosis and lack effective cure. Of those, parotid tumors constitute the majority. Functioning as metabolic machinery contributing to cellular redox balance, peroxisomes have emerged as crucial players in tumorigenesis.
我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门